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| SASAKI, Naoki; TSUZUKI, Nao; YAMADA, Michiaki; MINAMI, Takuto; YAMADA, Haruo; 佐々木, 直樹. |
| This study aimed to establish a standard dose and sample collection time for 13C phenylalanine and 13C-Dipeptide breath test in horses. To evaluate dose-dependent effects, healthy horses received 2.5 mg/kg, 5 mg/kg, and 10 mg/kg 13C phenylalanine dissolved in 1 ml/kg distilled water and 1.25 mg/kg, 2.5 mg/kg, and 5 mg/kg 13C dipeptide dissolved in 2 ml/kg distilled water. Tmax was observed during the sample collection time. For 13C phenylalanine, the standard deviation of Cmax at 5 mg/kg was lower than that of 10 mg/kg. For 13C dipeptide, the standard deviation of Tmax was the lowest at 5 mg/kg. This study revealed that an optimal dose for breath tests with 13C phenylalanine and 13C dipeptide may be 5 mg/kg in horses. |
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Palavras-chave: 13C-breath test; Dipeptide; Horses; Phenylalanine. |
| Ano: 2009 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3105 |
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