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| CHINCHILLA-CARMONA,MISAEL; VALERIO-CAMPOS,IDALIA; SÁNCHEZ-PORRAS,RONALD; MORA-CHAVES,VÍCTOR; BAGNARELLO-MADRIGAL,VANESSA; MARTÍNEZ-ESQUIVEL,LAURA; GONZÁLEZ-PANIAGUA,ANTONIETA; VANEGAS,JUAN CARLOS. |
| Se realizó una evaluación in vivo de la actividad antimalárica de las hojas, flores, frutos, corteza y raíz de 25 plantas de la Reserva Biológica Alberto Manuel Brenes (REBAMB), situada en San Ramón, Alajuela, Costa Rica. Las plantas estudiadas fueron Aphelandra aurantiaca (Scheidw.) Lindl., Aphelandra tridentata Hemsl. (Acanthaceae), Xanthosoma undipes (K. Koch & C.D. Bouché) K. Koch. (Araceae), Iriartea deltoidea Ruiz & Pav. (Arecaceae), Neurolaena lobata (L.) Cass. (Asteraceae), Lonchocarpus pentaphyllus (Poir.) Kunth ex DC., Pterocarpus hayesii Hemsl., Senna papillosa (Britton & Rose) H.S. Irwin & Barneby., Cinnamomum chavarrianum (Hammel) Kosterm. (Fabaceae), Nectandra membranacea (Sw.) Griseb., Persea povedae W.C.... |
| Tipo: Journal article |
Palavras-chave: Antimaláricos; Costa Rica; In vivo; Plantas; Plasmodium berghei. |
| Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-078X2011000100009 |
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| Gómez-Estrada,Harold; Gaitán-Ibarra,Ricardo; Díaz-Castillo,Fredyc; Pérez,Hilda A; Medina,José D. |
| Introduction: in vitro antimalarial activity of naphthoquinones (1-5), isolated from Tabebuia billbergii (Bureau & K. Schum.) Standl., was investigated. Tabebuia billbergii, commonly known as guayacán, is a plant traditionally used in the Amazon in numerous conditions like bacterial and fungal infections, fever, syphilis, malaria, trypanosomiasis, as well as stomach and bladder disorders, and tumours. Objective: to study the dichloromethane extracts of both the trunk and the inner bark of Tabebuia billbergii and to demonstrate the antimalarial activity of some of its bioactive components. Methods: some bioactive components were evaluated for the antimalarial activity against Plasmodium berghei, by using the inhibition of the differentiation cycle... |
| Tipo: Journal article |
Palavras-chave: Tabebuia billbergii; Naphthoquinones; Plasmodium berghei. |
| Ano: 2012 |
URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962012000200006 |
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| SILVA,Nazaré Carneiro da; GONÇALVES,Suellen Ferreira; ARAÚJO,Luciana Silva de; KASPER,Aline Aparecida München; FONSECA,Amanda Luisa da; SARTORATTO,Adilson; CASTRO,Kelly Christina Ferreira; MORAES,Tânia Mara Pires; BARATTO,Leopoldo Clemente; VAROTTI,Fernando de Pilla; BARATA,Lauro Euclides Soares; MORAES,Waldiney Pires. |
| ABSTRACT Malaria is a disease of global tropical distribution, being endemic in more than 90 countries and responsible for about 212 million cases worldwide in 2016. To date, the strategies used to eradicate this disease have been ineffective, without specific preventive measures such as vaccines. Currently, the existing therapeutic arsenal is limited and has become ineffective against the expansion of artemisinin-resistant Plasmodium, demonstrating the need for studies that would allow the development of new compounds against this disease. In this context, we studied the volatile oil obtained from rhizomes of Cyperus articulatus (VOCA), a plant species commonly found in the Amazon region and popularly used as a therapeutic alternative for the treatment of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antiplasmodial; Artemisinin resistance; Chloroquine resistance; Malaria; Plasmodium falciparum; Plasmodium berghei. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672019000400334 |
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