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Preparation and characterization of a novel antimicrobial film dressing for wound healing application BJPS
Gonçalves,Melissa Marques; Carneiro,Jaqueline; Justus,Barbara; Espinoza,Joel Toribio; Budel,Jane Manfron; Farago,Paulo Vitor; Paula,Josiane Padilha de.
Antibacterial activity and good mechanical properties are some of the characteristics required for an appropriate film dressing. A novel polymer blend was developed for wound healing application. Twenty-four formulations using the polymers chitosan, poly(vinyl alcohol) and/or ɛ-Polylysine and the plasticizer glycerol were designed using factorial design and then the films were prepared by the casting/solvent evaporation method. Seventeen films were obtained among the twenty-four proposed formulations that were characterized by Field Emission Scanning Electron Microscopy (FE-SEM) and Fourier Transform Infrared Spectroscopy (FTIR). Mechanical properties, such as tensile strength (σ), elongation at break (ɛ) and Young’s modulus (Y) as well as antibacterial...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chitosan; Poly(vinyl alcohol); Ɛ-Polylysine; Semi-occlusive dressing.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100631
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