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	Provedor de dados BJID (1) BJMBR (1) BJPS (1) Autor Antunes,Marina Venzon (1) Cai,Xuejiu (1) Castilhos,Juliana Kich (1) Cui,Junchang (1) Di,Xiuzhen (1) Dillenburg,Thaís Luise (1) Fagundes Neto,U. (1) Linden,Rafael (1) Liu,Youning (1) Machado,A.M.O. (1) Morais,M.B. (1) Ni,Wentao (1) Scaletsky,I.C.A. (1) Scribel,Letícia (1) Silva,L.Q.C.D. (1) Tahan,S. (1) Verza,Simone Gasparin (1) Wang,Rui (1) Wehba,J. (1) Wei,Chuanqi (1) Mais... Palavra-chave Polymyxin (3) Carbapenem-resistant (1) Carbapenemase-producing (1) Duodenal microflora (1) Enterobacteriaceae (1) Glucose solutions (1) Infants (1) Infectious diarrhea (1) LC-MS/MS (1) Saline solutions (1) Sepsis (1) Stability (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2020 (1) 2015 (1) 2007 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Efficacy of polymyxins in the treatment of carbapenem-resistant Enterobacteriaceae infections: a systematic review and meta-analysis BJID Ni,Wentao; Cai,Xuejiu; Wei,Chuanqi; Di,Xiuzhen; Cui,Junchang; Wang,Rui; Liu,Youning. In recent years, carbapenem-resistant Enterobacteriaceae has become endemic in many countries. Because of limited treatment options, the abandoned "old antibiotics", polymyxins, have been reintroduced to the clinic. To evaluate the clinical efficacy of polymyxins in the treatment of infections caused by carbapenem-resistant Enterobacteriaceae , we systemically searched the PubMed, Embase, and Cochrane Library databases and analyzed the available evidence. The Preferred Reporting Items for Systematic reviews and Meta-Analysis statement were followed, and the I 2 method was used for heterogeneity. Nineteen controlled and six single-arm cohort studies comprising 1086 patients met the inclusion criteria. For controlled studies, no significant difference was... Tipo: Info:eu-repo/semantics/article Palavras-chave: Polymyxin; Enterobacteriaceae; Carbapenem-resistant; Carbapenemase-producing. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000200170 A randomized double-blind clinical trial of the effect of non-absorbable oral polymyxin on infants with severe infectious diarrhea BJMBR Tahan,S.; Morais,M.B.; Wehba,J.; Scaletsky,I.C.A.; Machado,A.M.O.; Silva,L.Q.C.D.; Fagundes Neto,U.. The present study evaluated the effect of non-absorbable oral polymyxin on the duodenal microflora and clinical outcome of infants with severe infectious diarrhea. Polymyxin was chosen because classic enteropathogenic Escherichia coli was more sensitive to this antibiotic. Twenty-five infants were randomly assigned to a 7-day treatment with oral polymyxin (2.5 mg/kg in 4 daily doses) or placebo. Duodenal and stool cultures were performed before and after the treatment. Five patients were excluded during the study because of introduction of parental antibiotic therapy due to clinical sepsis (N = 3) or rapid clinical improvement (N = 2). In the polymyxin group, small bowel bacterial overgrowth occurred in 61.5% of the cases (8/13) before treatment and in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Infants; Infectious diarrhea; Duodenal microflora; Polymyxin; Sepsis. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200007 Evaluation of the stability of Polymyxin B in saline and glucose solutions using LC-MS/MS BJPS Castilhos,Juliana Kich; Dillenburg,Thaís Luise; Antunes,Marina Venzon; Scribel,Letícia; Zavascki,Alexandre Prehn; Linden,Rafael; Verza,Simone Gasparin. Polymyxins are a group of antibacterial substances and have remained the drugs of choice for treatment of resistant Gram-negative bacilli. Polymyxin B is administered by intravenous infusion and requires the reconstitution of lyophilized powder with 0.9% saline or 5% glucose solutions. To date, there is little information about polymyxin stability in different infusions solutions, especially at 40 ºC, a temperature that is recommended to study drug stability as it accelerates degradation reactions. Therefore, in this work an analytical method using LC-MS/MS was developed, validated and applied to determine the stability of polymyxin B diluted in 0.9% saline or 5% glucose solutions at 25 ºC and 40 ºC. The stability of polymyxin B solutions was evaluated... Tipo: Info:eu-repo/semantics/article Palavras-chave: Polymyxin; Stability; LC-MS/MS; Glucose solutions; Saline solutions. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100537 Registros recuperados: 3 Primeira ... 1 ... Última

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