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	Provedor de dados BJMBR (1) Autor Li,Na (1) Wu,Yanling (1) Xu,Gang (1) Xu,Rui (1) Zhang,Jinbiao (1) Zhang,Yan (1) Mais... Palavra-chave Gastric cancer (1) HDAC9 (1) MicroRNA-383-5p (1) Post-transcriptional regulation (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2019 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última MicroRNA-383-5p inhibits the progression of gastric carcinoma via targeting HDAC9 expression BJMBR Xu,Gang; Li,Na; Zhang,Yan; Zhang,Jinbiao; Xu,Rui; Wu,Yanling. MicroRNAs (miRNAs), as post-transcriptional regulators, have been reported to be involved in the initiation and progression of various types of cancer, including gastric cancer (GC). The present study aimed to investigate the role of miR-383-5p in gastric carcinogenesis. Cell viability was analyzed using CCK-8 kit. Annexin V-fluorescein isothiocyanate/propidium iodide double staining was used to evaluate cell apoptosis. The expression levels of miR-383-5p and histone deacetylase 9 (HDAC9) mRNA in GC tissues and cell lines were analyzed using RT-qPCR. The protein expression of HDAC9 was detected by western blotting. We found that HDAC9 was up-regulated and miR-383-5p was down-regulated in GC tissues and cell lines. High HDAC9 expression or low miR-383-5p... Tipo: Info:eu-repo/semantics/article Palavras-chave: MicroRNA-383-5p; Gastric cancer; HDAC9; Post-transcriptional regulation. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000800602 Registros recuperados: 1 Primeira ... 1 ... Última

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