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| LOPEZ-GARCIA,CARLOS; MOLOWNY,ASUNCION; NACHER,JUAN; PONSODA,XAVIER; SANCHO-BIELSA,FRANCISCO; ALONSO-LLOSA,GREGORI. |
| The medial cerebral cortex of lizards, an area homologous to the hippocampal fascia dentata, shows delayed postnatal neurogenesis, i.e., cells in the medial cortex ependyma proliferate and give rise to immature neurons, which migrate to the cell layer. There, recruited neurons differentiate and give rise to zinc containing axons directed to the rest of cortical areas, thus resulting in a continuous growth of the medial cortex and its zinc-enriched axonal projection. This happens along the lizard life span, even in adult lizards, thus allowing one of their most important characteristics: neuronal regeneration. Experiments in our laboratory have shown that chemical lesion of the medial cortex (affecting up to 95% of its neurons) results in a cascade of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Medial cortex; Hippocampus; Postnatal neurogenesis; Neural stem cells; Zinc; Regeneration. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000100006 |
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| Menezes,J.R.L.; Marins,M.; Alves,J.A.J.; Fróes,M.M.; Hedin-Pereira,C.. |
| New neurons are constantly added to the olfactory bulb of rodents from birth to adulthood. This accretion is not only dependent on sustained neurogenesis, but also on the migration of neuroblasts and immature neurons from the cortical and striatal subventricular zone (SVZ) to the olfactory bulb. Migration along this long tangential pathway, known as the rostral migratory stream (RMS), is in many ways opposite to the classical radial migration of immature neurons: it is faster, spans a longer distance, does not require radial glial guidance, and is not limited to postmitotic neurons. In recent years many molecules have been found to be expressed specifically in this pathway and to directly affect this migration. Soluble factors with inhibitory, attractive... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Postnatal neurogenesis; Chain migration; Rostral migratory stream; Astrocytes; Gap junctions; Radial glia. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001200002 |
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