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Effect of Resveratrol on Mitochondrial Activity in Differentiated Mature Adipocytes International Journal of Morphology
Noriega-González,J. E; Chirino,Y. I; Mata-Miranda,M. M; Vázquez-Zapién,G. J; Sánchez-Monroy,V.
Obesity has reached epidemic proportions, the World Health Organization (WHO) estimates that there are more than 1,000 million overweight adults world-wide. Furthermore, obesity is characterized as an overgrowth of white adipose tissue as a result of adipocyte hypertrophy and hyperplasia. Mitochondria is considered the source of energy within the adipocyte, since it contains the molecular machinery, and it is involved in a large number of metabolic pathways, besides the transformation of chemical energy into adenosine triphosphate. Mitochondria shortage and adipocyte dysfunction result in an excessive accumulation of triacylglycerol in the cytoplasm, which determines an imbalance between energy production and energy expenditure. Resveratrol (RSV) is a...
Tipo: Journal article Palavras-chave: Preadipocytes; Differentiated mature adipocyte; Mitochondrial activity; Resveratrol.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300044
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