|
|
|
| Registros recuperados: 90 | |
|
| |
|
|
| CORVINO,SILVANA B.; DAMASCENO,DÉBORA C.; SINZATO,YURI K.; NETTO,ALINE O.; MACEDO,NATHÁLIA C.D.; ZAMBRANO,ELENA; VOLPATO,GUSTAVO T.. |
| ABSTRACT The aim of this study was to compare two models of swimming applied to pregnant rats born small for pregnancy age (SPA). Diabetes was chemically induced in adult female rats to develop an inadequate intrauterine environment, leading to birth of a SPA offspring. In adulthood, the female SPA rats were mated and submitted to different swimming programs. The exercise program 1 (Ex1) consisted of swimming for 15 minutes, followed by 15 minutes of rest and another 15 minutes of swimming, 3 days a week before and during pregnancy. Another program (Ex2) was applied during 60 minutes uninterrupted a day, 6 days/week during pregnancy. The pregnant rats presented no interference on body weight and glycemia. The rats submitted to Ex2 model showed decreased... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rats; Diabetes; Pregnancy; Offspring; Exercise.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100223 |
| |
|
|
| SALVATIERRA,CRISTIANA S.B.; REIS,SÍLVIA R.L.; PESSOA,ANA F.M.; SOUZA,LETÍCIA M.I. DE; STOPPIGLIA,LUIZ F.; VELOSO,ROBERTO V.; REIS,MARISE A.B.; CARNEIRO,EVERARDO M.; BOSCHERO,ANTONIO C.; COLODEL,EDSON M.; ARANTES,VANESSA C.; LATORRACA,MÁRCIA Q.. |
| The phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways mediate β cell growth, proliferation, survival and death. We investigated whether protein restriction during pregnancy alters islet morphometry or the expression and phosphorylation of several proteins involved in the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways. As controls, adult pregnant and non-pregnant rats were fed a normal-protein diet (17%). Pregnant and non-pregnant rats in the experimental groups were fed a low-protein diet (6%) for 15 days. Low protein diet during pregnancy increased serum prolactin level, reduced serum corticosterone concentration and the expression of both protein kinase B/AKT1 (AKT1) and p70 ribosomal protein S6... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: MAP kinase pathway; Pancreatic islets; PI3K pathway; Pregnancy; Protein restriction; Rats. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000201007 |
| |
|
|
| Volpato,Gustavo T.; Francia-Farje,Luis A.D.; Damasceno,Débora C.; Oliveira,Renata V.; Hiruma-Lima,Clélia A.; Kempinas,Wilma G.. |
| Citrus aurantium L., commonly known as bitter orange, is widely used in folk medicine, but there is little data in the literature about the effects on pregnancy. The aim of the present study was to evaluate the influence of essential oil obtained from fruits of Citrus aurantium on the maternal reproductive outcome and fetal anomaly incidence in rats. Pregnant Wistar rats were randomized into four groups (n minimum = 12 animals/group): G1 = control, G2 to G4 = treated with essential oil from C. aurantium at dose 125, 250 and 500 mg/kg, respectively. Rats were orally treated, by gavage, with plant essential oil or vehicle during pre-implantation and organogenic period (gestational day 0-14). On gestational day 20 the rats were anaesthetized and the gravid... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Citrus aurantium; Essential oil; Limonene; Malformation; Pregnancy; Reproductive outcome. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100407 |
| |
|
|
| NETTO,ALINE OLIVEIRA; MACEDO,NATHÁLIA C.D.; GALLEGO,FRANCIANE Q.; SINZATO,YURI K.; VOLPATO,GUSTAVO T.; DAMASCENO,DÉBORA C.. |
| ABSTRACT Several studies present different methodologies and results about intensity exercise, and many of them are performed in male rats. However, the impact of different type, intensity, frequency and duration of exercise on female rats needs more investigation. From the analysis of blood lactate concentration during lactate minimum test (LacMin) in the swimming exercise, the anaerobic threshold (AT) was identified, which parameter is defined as the transition point between aerobic and anaerobic metabolism. LacMin test is considered a good indicator of aerobic conditioning and has been used in prescription of training in different exercise modalities. However, there is no evidence of LacMin test in female rats. The objective was to determine AT in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Exercise; Swimming; Anaerobic threshold; Lactate; Pregnancy; Rats. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000602749 |
| |
|
|
| Silva,M.O.; Ribeiro Filho,J.D.; Dantas,W.M.F.; Valente,F.L.; Ribeiro,B.M.; Ermita,P.A.N.; Monteiro,L.C.; Costa,C.M.; Silva,G.M.M.; Alves,S.R.; Avanza,M.F.B.; Santos,P.V.M.; Manso Filho,H.C.. |
| ABSTRACT The present study aimed to evaluate the effects of the transition period on hematological and biochemical constituents in Mangalarga Marchador mares. Forty-eight mares were used to form a maintenance group (MG) and transition group (TG), formed by pregnant mares and, after delivery, infants. Blood samples were collected at the following times: T-60 (60 d pre-delivery), T-30 (30 d pre-delivery), T-15 (15 d pre-delivery), T0 (first 6h post-delivery), T15 (15 d post-delivery), T30 (30 d post-delivery), and T60 (60 d post-delivery). The TG had lower values (P< 0.05) of red blood cells, hematocrit and hemoglobin at T0, T15, T30 and T60 times than MG. The mean corpuscular volume was lower in MG (P< 0.05) than in TG (T0, T15, T30 and T60) and mean... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Equine; Blood count; Lactation; Pregnancy; Peripartum. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000601765 |
| |
|
|
| Xavier,P.R.; Leão,R.A.C.; Oliveira e Silva,P.V.D.; Marques Júnior,A.P.. |
| Foram avaliadas características morfológicas do corpo lúteo de 48 vacas Nelore gestantes obtidos de abatedouros. Os ovários com o corpo lúteo foram coletados, identificados e divididos em três grupos, considerando o estágio da gestação determinado pelo tamanho do feto: Grupo I - onze animais com gestação até 90 dias; Grupo 2 - vinte animais com gestação de 90 a 180 dias, e Grupo 3 - 17 animais com gestação de 180 a 261 dias. Todos os corpos lúteos foram dissecados, submetidos a processamento histológico e avaliados utilizando microscopia de luz. As características morfológicas das células luteais esteroidogênicas não mudou durante a gestação. Porém, foi observado um aumento de tecido conjuntivo, fibroblastos e matriz extracelular durante o final da... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nelore cow; Pregnancy; Corpus luteum; Secretion granules. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000200036 |
| |
|
|
| Santarosa,B.P.; Lourenço,M.L.G.; Dantas,G.N.; Ulian,C.M.V.; Heckler,M.C.T.; Sudano,M.J.; Gonçalves,R.C.; Chiacchio,S.B.. |
| ABSTRACT There are studies on electrocardiogram (ECG) in several breeds of horses, which highlights the growing importance of cardiology in this species. But few authors have addressed the influence of pregnancy on the cardiac physiology of the mare, and specifically, there are no studies on the Mini-horse breed, as well as no correlation of body weight (BW) and heart rate (HR) with electrocardiographic parameters in this breed. The aims of this study were to determine the effects of pregnancy on ECG parameters and to examine the relationships between these variables and body weight (BW) and heart rate (HR). A total of 203 animals were used, including 143 females (66 pregnant) and 60 males. Electrocardiographic examinations were performed by computerized... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Horse; Body weight; Cardiology; Heart rate; Pregnancy. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000300579 |
| |
|
|
| Feliciano,M.A.R.; Silva,A.S.L.; Crivelaro,R.M.; Oliveira,M.E.F.; Coutinho,L.N.; Vicente,W.R.R.. |
| The aim of this study was to determine the profile of IL-2, IL-4, IL-10, IFN-γ, and TNF-α cytokines and KC-like cells (natural killer) in pregnant bitches, unpublished values for the species. A total of 27 females of the Shi Tzu, Pug, English Bulldog and French breeds, weighing 4-20kg and aged 4-6 years were used. Blood samples were collected from bitches during the anestrous and on the 2nd, 5th, 6th, 7th and 8th week of pregnancy. Serum levels of cytokines were measured by panel MILLIPLEX MAP (CCYTO-90K, MILLIPORE, Billerica, Massachusetts, USA) validated for dogs. Twenty four females showed physiological pregnancy and three bitches showed pathological pregnancy. There was no difference between cytokine values during anestrous and gestational weeks of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dog; Immunity; Pregnancy. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000401067 |
| |
|
| |
|
|
| Zhang,Lian-Dong; Deng,Qian; Wang,Zi-Ming; Gao,Ming; Wang,Lei; Chong,Tie; Li,He-Cheng. |
| Studies of developmental effects of mixtures of endocrine disrupters on the male reproductive system are of great concern. In this study, the reproductive effects of the co-administration of di-2-(ethylhexyl) phthalate (DEHP) and genistein (GEN) during pregnancy and lactation were studied in male rat offspring. Pregnant Sprague-Dawley rats were gavaged from gestation day 3 to postnatal day 21 with vehicle control, DEHP 250 mg/kg body weight (bwyday, GEN 50 mg/kg bwday, GEN 400 mg/kg bwday, and two combinations of the two compounds (DEHP 250 mg/kg bwday + GEN 50 mg/kg bwday, DEHP 250 mg/kg bwday + GEN 400 mg/kg bwday). The outcomes studied were general morphometry (weight, AGD), testicular histology, testosterone levels, and expression at the mRNA level of... |
| Tipo: Journal article |
Palavras-chave: Di-2-(ethylhexyl) phthalate; Genistein; Pregnancy; Lactation; Reproductive system. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000200004 |
| |
|
| |
|
| |
|
|
| Damasceno,Débora Cristina; Volpato,Gustavo Tadeu; Ferrari,Cássio; Roldan,Luciana B.; Souza,Maricelma da Silva Soares. |
| The objective of this study was to evaluate the reproductive performance, liver morphological study and post mortem characteristics of the pregnant Wistar rats treated with indomethacin, a general COX inhibitor. Indomethacin at doses of 0 (control), 0.32, 1.68 and 8.40 mg/kg/day were orally given once daily to each group (n=10) on days 3 and 4 of pregnancy (day 0 = first day of pregnancy = positive vaginal sperm). The animals were euthanized under anesthesia on day 11 of pregnancy, and were carried out necropsy and microorganism culture study. The results showed that the doses of 0.32 and 1.68 mg/kg body weight (the therapeutic dose for humans) of indomethacin caused no embryotoxic or lethal effects. The highest dose (8.40 mg/kg) of indomethacin disturbed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Indomethacin; COX; Pregnancy; Rat; Implantation. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000100010 |
| |
|
| |
|
|
| Iessi,Isabela Lovizutto; Bueno,Aline; Sinzato,Yuri Karen; Spada,Ana Paula Machado; Rudge,Marilza Vieira Cunha; Heubel,Maricê Thereza Correa Domingues; Damasceno,Débora Cristina. |
| The aim of this sstudy was to evaluate the liver glycogen storage in pregnant rats presenting neonatal streptozotocin-induced diabetes and to establish a relation with glycemia and insulin levels. Wistar rats were divided in to two groups: 1) Mild Diabetes (STZ) - received streptozotocin (glycemia from 120 to 300 mg/dL), 2) Control - received vehicle (glycemia below 120 mg/dL). At days 0, 7, 14 and 21 of the pregnancy, body weight and glycemia were evaluated. At day 21 of the pregnancy, the rats were anesthetized for blood and liver collection so as to determine insulin and liver glycogen, which showed no changes in the STZ group as compared to the controls. In the STZ group, maternal weight gain were lower as compared to those in the control group.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pregnancy; Rat; Hyperglycemia; Glycogen storage liver; Mild diabetes; Hyperglycemia. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000200010 |
| |
|
|
| Machado,Ana Lourdes da Silva; Brandão,Adriana Aigotti Haberbeck; Silva,Cláudia Maria de Oliveira Monteiro da; Rocha,Rosilene Fernandes da. |
| This study aimed on evaluating the possible effects of tetracycline administered to rats on the tenth day of pregnancy, on kidney and liver development of their offspring. The liver showed vacuolization, necrosis, inflammation and sinusoidal dilatations, more evident in the newborn. Mitosis, early increase of Kupffer cells population and hipertrophy of hepatocytes with greater synthesis of glycogen were present on the tenth and twentieth days of life. The kidney showed slight tubular vacuolizations and necrosis, more proeminent in the newborn, as well as signs of tubular regeneration on the tenth and twentieth days. These results suggested that the organs studied went through several transitory morphological changes during development but presented signs... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pregnancy; Development; Tetracycline; Hepatotoxicity; Nephrotoxicity. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132003000100008 |
| |
|
|
| Consonni,Marcos; Damasceno,Débora Cristina; Kempinas,Wilma De Grava; Nassr,Azize Cristina Capelli; Volpato,Gustavo Tadeu; Dallaqua,Bruna; Iessi,Isabela Lovizutto; Saito,Felipe Hiroshi; Calderon,Iracema Mattos Paranhos; Rudge,Marilza Vieira Cunha. |
| The aim of this work was to evaluate the direct protective action of oral fatty acid supplementation against the deleterious effect of hyperglycemia on maternal reproductive outcomes; fetal growth and development on female Wistar rats. The animals were distributed into four experimental groups: G1= non-diabetic without supplementation (Control group); G2= non-diabetic treated with linoleic (LA) and gammalinolenic acid (GLA) (1 mL of Gamaline-V/day); G3= diabetic without supplementation and G4= diabetic treated with LA and GLA. Diabetes was induced by streptozotocin (40 mg/kg). At day 21 of pregnancy, the gravid uterus was weighed and dissected to count the dead and live fetuses, resorption, implantation, and corpora lutea numbers. The fetuses were analyzed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Diabetes; Rat; Pregnancy; Anomalies; Fatty acid supplementation; Gamaline-V. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000500008 |
| |
|
|
| Brazdova,Andrea; Keprova,Alena; Zidkova,Jarmila; Madar,Jindrich. |
| Pre-eclampsia is a serious pathological state affecting 5-10% of pregnant women. Currently, it is diagnosed in the second half of pregnancy, particularly after the 20th week. Symptoms mostly correspond to the changes of blood vessels and kidneys. The severity of pre-eclampsia is proportional to symptomatic manifestations, thus the more symptoms present, the higher is of pre-eclampsia development. Although there are several studies dealing with pre-eclampsia pathology, the complete etiology is still unknown. In this review paper, several theories are presented and discussed. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Placenta; Pre-eclampsia; Pregnancy; Oxidative stress. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000500701 |
| |
| Registros recuperados: 90 | |
|
|
|
