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Risk factors for ovarian failure in patients with systemic lupus erythematosus BJMBR
Medeiros,M.M.C.; Silveira,V.A.L.; Menezes,A.P.T.; Carvalho,R.C..
The aim of the present study was to identify the risk factors for ovarian failure in patients with systemic lupus erythematosus. Seventy-one women aged 17 to 45 years with systemic lupus erythematosus were studied. Patients were interviewed and their medical records reviewed. Demographic characteristics, clinical and serologic profiles, and menstrual and obstetric histories were recorded. Disease activity was measured by the systemic lupus erythematosus disease activity index. Serum FSH, LH, estradiol, progesterone, TSH, prolactin, and antimicrosomal and antithyroglobulin antibodies were measured. Patients who developed ovarian failure were compared to those who did not. Ovarian failure occurred in 11 patients (15.5%) and nine had premature menopause...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ovarian failure; Systemic lupus erythematosus; Risk factors; Cyclophosphamide; Premature menopause.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001200008
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Women with primary ovarian insufficiency have lower bone mineral density BJMBR
Amarante,F.; Vilodre,L.C.; Maturana,M.A.; Spritzer,P.M..
The aim of the present study was to assess the prevalence of osteoporosis in a sample of 32 patients with spontaneous primary ovarian insufficiency (POI) in comparison to reference groups of 25 pre- and 55 postmenopausal women. Hip (lumbar) and spinal bone mineral density (BMD) measurements were performed by dual-energy X-ray absorptiometry in the three groups. The median age of POI patients at the time of diagnosis was 35 years (interquartile range: 27-37 years). The mean ± SD age of postmenopausal reference women (52.16 ± 3.65 years) was higher than that of POI (46.28 ± 10.38 years) and premenopausal women (43.96 ± 7.08; P = 0.001) at the time of BMD measurement. Twenty-seven (84.4%) POI women were receiving hormone replacement therapy (HRT) at the time...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Premature ovarian failure; Premature menopause; Osteoporosis; Bone mineral density; Hypogonadism.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000100012
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