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Frequency of primary glomerular disease in northeastern China BJMBR
Wu,Yi-Qi; Wang,Zheng; Xu,Hua-Feng; Jin,Xiao-Ming; Zhou,Hai-Zhou.
Most frequently reported Chinese renal biopsy data have originated from southeastern China. The present study analyzed the renal biopsy data from northeastern China. The records of 1550 consecutive native patients who were diagnosed with primary glomerular diseases (PGD) after renal biopsy at our hospital during 2005-2009 were used. These patients were divided into four age groups for stratified analysis: <15, 15-44, 45-59, and ≥60 years old. Among PGD, minimal change disease (MCD) was the most common histologically diagnosed disease (30.7%), followed by IgA nephropathy (IgAN), mesangial proliferative glomerulonephritis (MsPGN), membranous nephropathy (MN), membranoproliferative glomerulonephritis (MPGN), focal segmental glomerulosclerosis (FSGS), and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Primary glomerular disease; Renal biopsies; IgA nephropathy; China.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000800011
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Cyclophosphamide in the treatment of focal segmental glomerulosclerosis BJMBR
Martinelli,R.; Pereira,L.J.; Silva,O.M.M.; Okumura,A.S.; Rocha,H..
Prednisone is the initial treatment of primary focal segmental glomerulosclerosis. However, when immunosuppressive agents in combination with steroids are used in the treatment of prednisone-dependent and prednisone-resistant patients the remission rate is variable. We report a long-term trial using cyclophosphamide (2.0 to 3.0 mg/kg body weight for 12 weeks) in combination with prednisone (1.0 to 2.0 mg/kg body weight), as compared with prednisone alone for the treatment of prednisone-resistant and frequently relapsing nephrotic syndrome and focal segmental glomerulosclerosis. Fifty-four patients (34 males and 20 females) with a diagnosis of idiopathic nephrotic syndrome and focal segmental glomerulosclerosis, followed-up for an average of 86.1 ± 82.4...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cyclophosphamide; Prednisone; Nephrotic syndrome; Primary glomerular disease; Focal segmental glomerulosclerosis.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000900011
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