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| Registros recuperados: 1.768 | |
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| Donnelly,J.J.; Ulmer,J.B.. |
| DNA plasmids encoding foreign proteins may be used as immunogens by direct intramuscular injection alone, or with various adjuvants and excipients, or by delivery of DNA-coated gold particles to the epidermis through biolistic immunization. Antibody, helper T lymphocyte, and cytotoxic T lymphocyte (CTL) responses have been induced in laboratory and domesticated animals by these methods. In a number of animal models, immune responses induced by DNA vaccination have been shown to be protective against challenge with various infectious agents. Immunization by injection of plasmids encoding foreign proteins has been used successfully as a research tool. This review summarizes the types of DNA vaccine vectors in common use, the immune responses and protective... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Plasmid; Nucleic acid; Protection; Antibodies; T cells; CTL. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000200010 |
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| Umekita,L.F.; Ramos,D.P.; Mota,I.. |
| A study was conducted on mice infected with strains Y and CL of Trypanosoma cruzi. The ability of anti-Y and anti-CL sera to induce complement-mediated lysis, immune clearance and protection against the acute phase of the infection was studied using homologous anti-Y or anti-CL serum tested with the Y or CL strain, or heterologous anti-Y serum tested with the CL strain or anti-CL serum tested with the Y strain. Complement-mediated lysis was induced by both homologous and heterologous antisera but protection was afforded only by homologous antisera. Immune clearance was induced by homologous but not by heterologous antisera. Antisera with high clearance ability were able to confer protection whereas antisera with high lytic ability were not. These results... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Trypanosoma cruzi; Clearance; Complement-mediated lysis; Protection. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000009 |
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| To study the effect of halothane as a cardioplegic agent, ten Wistar rats were anesthetized by ether inhalation and their hearts were perfused in a Langendorff system with Krebs-Henseleit solution (36oC; 90 cm H2O pressure). After a 15-min period for stabilization the control values for heart rate, force (T), dT/dt and coronary flow were recorded and a halothane-enriched solution (same temperature and pressure) was perfused until cardiac arrest was obtained. The same Krebs-Henseleit solution was reperfused again and the parameters studied were recorded after 1, 3, 5, 10, 20 and 30 min. Cardiac arrest occurred in all hearts during the first two min of perfusion with halothane-bubbled solution. One minute after reperfusion without halothane, the following... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Cardioplegia; Myocardial; Protection; Halothane. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000600009 |
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| Gerard, Andre; Thouard, Emmanuel; Veron, Gerard; Denis, Jacques; Thebaud, Olivier. |
| The "Artificial reefs" and "Repopulating" issues have been tackled by the Ifremer for a number of years without reaching a clear cut point of view, mainly for lack of socio-economic elements necessary to a rigorous analysis of these devices and practices. During a mission in Japan in January 2006, some Japanese experts, have presented to the head of the Ifremer a few examples of realisations related to these fields and conducted in their country. The head of the Ifremer realised the scope of such devices in Japan and expressed the wish to see an in-depth study carried out over there. In this purpose, the International Relationship Department organised and co-financed the three-month stay in Japan of a student from the University of Montpellier III, Sylvain... |
| Tipo: Text |
Palavras-chave: France; Etranger; Recommandations; Réglementation; Cadre juridique; Protection; Aménagement; Intérêt; Ecosystème; Récifs artificiels. |
| Ano: 2008 |
URL: http://archimer.ifremer.fr/doc/2008/rapport-6533.pdf |
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| Gawel, Mj. |
| Guam consists of a single main island surrounded by shallow fringing coral reefs. The marine species and ecology of Guam's coral reefs have been studied extensively, especially through programs of the University of Guam's Marine Laboratory. In addition to overfishing and destructive fishing practices, the marine benthic communities of Guam have been damaged by major storm waves; loss of corals to crown of thorns starfish predation; damage by recreational swimmers, divers and watercraft operators; grounding of ships and pollutant discharges of sewage and of stormwater. But the most serious damage is due to accelerated siltation, sedimentation and turbidity due to erosion related to land use practices. Steps are being taken to protect Guam's coral reefs and... |
| Tipo: Text |
Palavras-chave: Récif; Protection; Benthique; Environnement; Guam; Reef; Protection; Benthic; Environment; Guam. |
| Ano: 1999 |
URL: http://archimer.ifremer.fr/doc/00325/43595/44036.pdf |
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| Namangala, Boniface; Inoue, Noboru; Sugimoto, Chihiro; 井上, 昇. |
| Transforming growth factor beta-1 (TGF-β1) is a pleiotropic cytokine with both pro- and antiinflammatory properties, depending on its environment and concentration. The present study evaluated the effects of orally-delivered TGF-β1 on mice parenterally-infected with various protozoan parasites. We report that while orally-administered TGF-β1 seems to confer partial protection against murine chronic babesiosis and acute trypanosomosis, no beneficial clinical effects were observed against acute babesiosis, malaria or toxoplasmosis. Taken together, these preliminary data suggest that the systemic effects conferred by exogenous TGF-β1 could be parasite speciesspecific. The variations in different parasitic infections could be due to (i) intrinsic differences... |
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Palavras-chave: Low-dose; Mice; Orally-delivered TGF-β1; Protection; Protozoan parasites. |
| Ano: 2009 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2716 |
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| Palma, J. R.; Betanzos, A.E.; Puga, R.; Alzugaray, R.. |
| Ante la alta incidencia de langostas sublegales en las capturas de la región nororiental de Cuba, la cual se efectúa en casi 70 % con nasas, se diseñó y ejecutó un experimento para determinar la influencia de diferentes ventanas de escape de 53, 55 y 57 mm de alto por 440 mm de largo, en la evasión de langostas sublegales y de otras especies marinas capturadas de forma incidental. Los análisis estadísticos (Anova) demuestran que no se presentan diferencias significativas (p > 0,05) entre el largo y el alto del cefalotórax entre hembras y machos; las curvas de selectividad basadas en el escape de langostas de talla conocida a través de los tres altos de ventana, muestran que la ventana de 55 mm de alto presenta los mejores resultados para la actual talla... |
| Tipo: Preprint |
Palavras-chave: Lobster fisheries; Protection. |
| Ano: 2010 |
URL: http://hdl.handle.net/1834/3622 |
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| Registros recuperados: 1.768 | |
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