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	Provedor de dados Biol. Res. (2) Autor BARRO,MARIO (1) FERNÁNDEZ,JORGE (1) GALENO,HÉCTOR (1) MARTÍNEZ,RODRIGO (1) MORA,JUDITH (1) MORALES,JAIME L (1) MÜLLER,ILSE (1) RAMÍREZ,EUGENIO (1) RICARDO,ALBA (1) ROSEMBLATT,MARIO (1) SPENCER,EUGENIO (1) TISCHLER,NICOLE D (1) VALENZUELA,PABLO D.T. (1) VILLAGRA,ELIECER (1) VÁSQUEZ-DEL CARPIÓ,RODRIGO (1) Mais... Palavra-chave RNA polymerase (2) Bioinformatic analysis (1) Genome replication (1) Genome sequence (1) Hantavirus (1) Human isolate (1) Rotavirus (1) Mais... Tipo do documento Journal article (2) Ano 2006 (1) 2003 (1) País Chile (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Complete sequence of the genome of the human isolate of Andes virus CHI-7913: comparative sequence and protein structure analysis Biol. Res. TISCHLER,NICOLE D; FERNÁNDEZ,JORGE; MÜLLER,ILSE; MARTÍNEZ,RODRIGO; GALENO,HÉCTOR; VILLAGRA,ELIECER; MORA,JUDITH; RAMÍREZ,EUGENIO; ROSEMBLATT,MARIO; VALENZUELA,PABLO D.T.. We report here the complete genomic sequence of the Chilean human isolate of Andes virus CHI-7913. The S, M, and L genome segment sequences of this isolate are 1,802, 3,641 and 6,466 bases in length, with an overall GC content of 38.7%. These genome segments code for a nucleocapsid protein of 428 amino acids, a glycoprotein precursor protein of 1,138 amino acids and a RNA-dependent RNA polymerase of 2,152 amino acids. In addition, the genome also has other ORFs coding for putative proteins of 34 to 103 amino acids. The encoded proteins have greater than 98% overall similarity with the proteins of Andes virus isolates AH-1 and Chile R123. Among other sequenced Hantavirus, CHI-7913 is more closely related to Sin Nombre virus, with an overall protein... Tipo: Journal article Palavras-chave: Hantavirus; Genome sequence; RNA polymerase; Human isolate. Ano: 2003 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602003000200010 Bioinformatic prediction of polymerase elements in the rotavirus VP1 protein Biol. Res. VÁSQUEZ-DEL CARPIÓ,RODRIGO; MORALES,JAIME L; BARRO,MARIO; RICARDO,ALBA; SPENCER,EUGENIO. Rotaviruses are the major cause of acute gastroenteritis in infants world-wide. The genome consists of eleven double stranded RNA segments. The major segment encodes the structural protein VP1, the viral RNA-dependent RNA polymerase (RdRp), which is a minor component of the viral inner core. This study is a detailed bioinformatic assessment of the VP1 sequence. Using various methods we have identified canonical motifs within the VP1 sequence which correspond to motifs previously identified within RdRps of other positive strand, double-strand RNA viruses. The study also predicts an overall structural conservation in the middle region that may correspond to the palm subdomain and part of the fingers and thumb subdomains, which comprise the polymerase core of... Tipo: Journal article Palavras-chave: Rotavirus; Genome replication; RNA polymerase; Bioinformatic analysis. Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000500008 Registros recuperados: 2 Primeira ... 1 ... Última

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