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| Teixeira,Santuza M.; Paiva,Rita Márcia Cardoso de; Kangussu-Marcolino,Monica M.; DaRocha,Wanderson D.. |
| In 2005, draft sequences of the genomes of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major, also known as the Tri-Tryp genomes, were published. These protozoan parasites are the causative agents of three distinct insect-borne diseases, namely sleeping sickness, Chagas disease and leishmaniasis, all with a worldwide distribution. Despite the large estimated evolutionary distance among them, a conserved core of ~6,200 trypanosomatid genes was found among the Tri-Tryp genomes. Extensive analysis of these genomic sequences has greatly increased our understanding of the biology of these parasites and their host-parasite interactions. In this article, we review the recent advances in the comparative genomics of these three species. This analysis also... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Trypanosoma brucei; Trypanosoma cruzi; Leishmania major; Genome; RNAseq. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000100001 |
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| Vagner, Marie; Pante, Eric; Viricel, Amelia; Lacoue-labarthe, Thomas; Zambonino-infante, Jose-luis; Quazuguel, Patrick; Dubillot, Emmanuel; Huet, Valerie; Le Delliou, Herve; Lefrançois, Christel; Imbert-auvray, Nathalie. |
| Highly unsaturated fatty acids of the omega-3 series (HUFA) are major constituents of cell membranes, yet poorly synthesised de novo by consumers. Their production, mainly supported by aquatic microalgae, has been decreasing with global change. Understanding the consequences of such reductions is essential for ectotherm consumers, since temperature tightly regulates the HUFA content in cell membranes, maintaining their functionality. Integrating individual, tissue and molecular approaches, we examined the consequences of the combined effects of temperature and HUFA depletion on the key cardio-respiratory functions of the golden grey mullet, an ectotherm grazer of high ecological importance. For four months, fish were exposed to two contrasting HUFA diets... |
| Tipo: Text |
Palavras-chave: Omega-3 highly unsaturated fatty acids; Temperature; Cardiac performance; Swimming performance; Chelon auratus; RNAseq. |
| Ano: 2019 |
URL: https://archimer.ifremer.fr/doc/00476/58744/63565.pdf |
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| Artigaud, Sebastien; Thorne, Michael A. S.; Richard, Joelle; Lavaud, Romain; Jean, Fred; Flye-sainte-marie, Jonathan; Peck, Lloyd S.; Pichereau, Vianney; Clark, Melody S.. |
| RNA-Seq transcriptome data were generated from mantle tissue of the great scallop, Pecten maximus. The consensus data were produced from a time course series of animals subjected to a 56-day thermal challenge at 3 different temperatures. A total of 26,064 contigs were assembled de novo, providing a useful resource for both the aquaculture community and researchers with an interest in mollusc shell production. |
| Tipo: Text |
Palavras-chave: Pecten maximus; RNAseq; Temperature. |
| Ano: 2014 |
URL: https://archimer.ifremer.fr/doc/00202/31362/82662.pdf |
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