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A menu-driven facility for complex sample size calculation in randomized controlled trials with a survival or a binary outcome: Update AgEcon
Barthel, Friederike Maria-Sophie; Royston, Patrick; Babiker, Abdel.
Royston and Babiker (2002) presented a menu-driven Stata program for the calculation of sample size or power for complex clinical trial designs under a survival time or binary outcome. In the present article, the package is updated to Stata 8 under the new name ART. Furthermore, the program has been extended to incorporate noninferiority designs and provides more detailed output. This package is the only realistic sample size tool for survival studies available in Stata.
Tipo: Journal Article Palavras-chave: Sample size; Power; Randomized controlled trial; Multiarm designs; Survival analysis; Research Methods/ Statistical Methods.
Ano: 2005 URL: http://purl.umn.edu/117503
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Graphical representation of interactions AgEcon
Barthel, Friederike Maria-Sophie; Royston, Patrick.
We provide a program to illustrate interactions between treatment and covariates or between two covariates by using forest plots under either the Cox proportional hazards or the logistic regression model. The program is flexible in both the possibility of illustrating more than one interaction at a time and variable specifications of scale.
Tipo: Journal Article Palavras-chave: Fintplot; Interaction; Forest plot; Randomized controlled trial; Survival analysis; Logistic regression; Research Methods/ Statistical Methods.
Ano: 2006 URL: http://purl.umn.edu/117585
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Long-term efficacy of a rural community-based integrated intervention for prevention and management of chronic obstructive pulmonary disease: a cluster randomized controlled trial in China's rural areas BJMBR
Yuan,X.; Tao,Y.; Zhao,J.P.; Liu,X.S.; Xiong,W.N.; Xie,J.G.; Ni,W.; Xu,Y.J.; Liu,H.G..
This study aimed to assess the efficacy of a rural community-based integrated intervention for early prevention and management of chronic obstructive pulmonary disease (COPD) in China. This 18-year cluster-randomized controlled trial encompassing 15 villages included 1008 patients (454 men and 40 women in the intervention group [mean age, 54 ± 10 years]; 482 men and 32 women in the control group [mean age, 53 ± 10 years]) with confirmed COPD or at risk for COPD. Villages were randomly assigned to the intervention or the control group, and study participants residing within the villages received treatment accordingly. Intervention group patients took part in a program that included systematic health education, smoking cessation counseling, and education on...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronic obstructive pulmonary disease; Randomized controlled trial; Integrated intervention; Rural area; Lung function; Smoking cessation.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001101023
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Randomized controlled trials of serotonin-norepinephrine reuptake inhibitor in treating major depressive disorder in children and adolescents: a meta-analysis of efficacy and acceptability BJMBR
Xu,Y.; Bai,S.J.; Lan,X.H.; Qin,B.; Huang,T.; Xie,P..
New generation antidepressant therapies, including serotonin-norepinephrine reuptake inhibitor (SNRIs), were introduced in the late 1980s; however, few comprehensive studies have compared the benefits and risks of various contemporary treatments for major depressive disorder (MDD) in young patients. A comprehensive literature search of PubMed, Cochrane, Embase, Web of Science, and PsycINFO databases was conducted from 1970 to January 2015. Only clinical trials that randomly assigned one SNRI or placebo to patients aged 7 to 18 years who met the diagnostic criteria for major depressive disorder were included. Treatment success, dropout rate, and suicidal ideation/attempt outcomes were measured. Primary efficacy was determined by pooling the risk ratios...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adolescent; Child; Major depressive disorder; Meta-analysis; Randomized controlled trial; Serotonin and norepinephrine reuptake inhibitor.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000600704
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