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	Provedor de dados BJPS (1) Autor Bhalekar,Mangesh Ramesh (1) Gawale,Nitin Somnath (1) Kadam,Nitin Madhukar (1) Madgulkar,Ashwini (1) Patil,Nilam Hindurao (1) Palavra-chave Domperidone/sustained release (1) Domperidone/tablets (1) Drugs/delivery system (1) Fármacos/sistema de liberação (1) Ion exchange resins/drugs delivery system (1) Ion exchange resins/use (1) Ranitidine/immediate release (1) Ranitidine/tablets (1) Tablets/delivery system (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2010 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Novel ion exchange resin-based combination drug-delivery system for treatment of gastro esophageal reflux diseases BJPS Bhalekar,Mangesh Ramesh; Kadam,Nitin Madhukar; Patil,Nilam Hindurao; Gawale,Nitin Somnath; Madgulkar,Ashwini. The present study involves preparation and characterization of a combination tablet of ranitidine in immediate release form and domperidone in sustained release form, using ion exchange resins. Ranitidine lowers acid secretion, while domperidone release over a prolonged period improves gastric motility thus justifying this combination in gastro esophageal reflux diseases (GERD) and ensuring patient compliance. Drug loading was carried out by batch method & resinates were characterized using FTIR, XRPD. Resinates were formulated as a combination tablet and evaluated for tablet properties & in vitro drug release. Resinates provided sustained release of domperidone and immediate release of ranitidine. IR and X-ray studies indicate complexation... Tipo: Info:eu-repo/semantics/article Palavras-chave: Drugs/delivery system; Ranitidine/tablets; Ranitidine/immediate release; Domperidone/tablets; Domperidone/sustained release; Tablets/delivery system; Ion exchange resins/use; Ion exchange resins/drugs delivery system; Fármacos/sistema de liberação. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200021 Registros recuperados: 1 Primeira ... 1 ... Última

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