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Quantitative studies of the vasculature of the carotid body in the chronically hypoxic rat BJMBR
Clarke,J.A.; Daly,M. de B.; Marshall,J.M.; Ead,H.W.; Hennessy,E.M..
The carotid bodies of rats made chronically hypoxic by breathing 12% O2 in a normobaric chamber (inspired PO2 91 mmHg) were compared with those of controls. Serial 5-µm sections of the organs were examined using an interactive image analysis system. The total volume of the carotid bodies was increased by 64%. The total vascular volume rose by 103% and was likely due to an increase in size of the large vessels (>12 µm lumen diameter) because the small vessel (5-12 µm lumen diameter) volume did not increase significantly while the small vessel density tended to decrease. The extravascular volume was increased by 57%. Expressed as a percentage of the total volume of the organ, the total vascular volume did not change, but the small vessel volume was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rat carotid body; Morphology; Chronic hypoxia.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000300012
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