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MOURA,ELVIANI B.; PETZHOLD,SILVIA V.; AMARAL,AUGUSTO R.; DEBONI,LUCIANE M.; FRANÇA,PAULO H.C. DE. |
ABSTRACT The BK virus (BKV) produces a subclinical kidney infection in immunocompetent individuals. However, viremia may occur in kidney transplant patients with ongoing immunosuppression. BKV-associated nephropathy (BKVN) has no specific treatment and is a leading cause of organ transplant loss. In this study, we evaluated the predisposition and the clinical impact of BKV replication in kidney transplant patients during post-transplant monitoring in a reference institution in Brazil. Demographic, clinical and laboratory data generated during routine outpatient follow-up were retrospectively collected. BK viremia was investigated using real-time polymerase chain reaction. Of the 553 participants, 7.4% (n = 41) presented BKV replication. Of these, 16 (39%)... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: BK virus; Nephropathy; Renal transplantation; Viremia. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000200675 |
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Emori,Christini Takemi; Perez,Renata Melo; Matos,Carla Adriana Loureiro de; Uehara,Silvia Naomi Oliveira; Pereira,Patricia da Silva Fucuta; Feldner,Ana Cristina Amaral; Carvalho Filho,Roberto José de; Silva,Ivonete Sandra de Souza e; Silva,Antonio Eduardo Benedito; Ferraz,Maria Lucia Gomes. |
Introduction:There is scarce information regarding clinical evolution of HBV infection in renal transplant patients.Aims:To evaluate the prevalence of acute exacerbation in HBV-infected renal transplant patients and its association with the time after transplantation, presence of viral replication, clinical evolution, and use of antiviral prophylaxis.Materials and methods:HBV infected renal transplant patients who underwent regular follow-up visits at 6-month intervals were included in the study. The criteria adopted to characterize exacerbation were: ALT >5 × ULN and/or >3 × baseline level. Predictive factors of exacerbation evaluated were age, gender, time on dialysis, type of donor, post-transplant time, ALT, HBeAg, HBV-DNA, HCV-RNA,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Renal transplantation; Hepatitis B; ALT flare; Lamivudine. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600625 |
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Abboud,Cely S.; Bergamasco,Maria Daniela; Sousa,Ercilia Evangelista de; Zandonadi,Eliana de Cássia; Cortez,Doralice. |
At our institution, we observed an increase in the incidence of healthcare-associated infections (HAI) due to Gram-negative bacilli, including three cases of carbapenem-resistant Klebsiella pneumoniae, among patients who underwent renal transplantation. In addition to strengthening infection control measures, we chose to add gentamycin to the antibiotic prophylaxis regimen of patients undergoing renal transplantation. We assessed the number of HAI occurring within 30 days of renal transplantation during two time periods: (1) the preintervention period, between September 2009 and June 2010, and (2) the post-intervention period, between July 2010 and April 2011. The intervention consisted of the addition of gentamycin to the surgical antibiotic prophylaxis... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Renal transplantation; Antibiotic prophylaxis; Gentamycin; Health-care associated infections. |
Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000200021 |
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Abdallah,K.A.; Jorgetti,V.; Pereira,R.C.; dos Reis,L.M.; Pereira,L.M.; Corrêa,P.H.S.; Borelli,A.; Ianhez,L.E.; Moysés,R.M.A.; David-Neto,E.. |
Low bone remodeling and relatively low serum parathyroid hormone (PTH) levels characterize adynamic bone disease (ABD). The impact of renal transplantation (RT) on the course of ABD is unknown. We studied prospectively 13 patients with biopsy-proven ABD after RT. Bone histomorphometry and bone mineral density (BMD) measurements were performed in the 1st and 12th months after RT. Serum PTH, 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, and osteocalcin were measured regularly throughout the study. Serum PTH levels were slightly elevated at transplantation, normalized at the end of the third month and remained stable thereafter. Bone biopsies performed in the first month after RT revealed low bone turnover in all patients, with positive bone aluminum staining... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Adynamic bone disease; Aluminum bone disease; Bone biopsy; Parathormone; Renal osteodystrophy; Renal transplantation. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000100004 |
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