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Spi2 gene polymorphism is not associated with recurrent airway obstruction and inflammatory airway disease in thoroughbred horses Genet. Mol. Biol.
Silva,Aline Correa da; Brass,Karin Erica; Loreto,Elgion da Silva; Vinocur,Myriam Elizabeth; Pozzobon,Ricardo; Azevedo,Marcos da Silva.
The aim was to detect the presence of polymorphisms at exons 1, 2, 3 and 4 of the Spi2 gene, and evaluate a possible association between them and recurrent airway obstruction (RAO) or inflammatory airway disease (IAD) in thoroughbred horses, through single-strand conformational-polymorphism (SSCP) screening. Although polymorphism was not detected in exons 1, 2 and 3, three alleles and six genotypes were identified in exon 4. The frequencies of allele A (0.6388) and genotype AA (0.3888) were higher in horses affected by RAO, although no association was found between polymorphism and horses with either RAO or IAD.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Horse; Respiratory disease; SSCP; Alpha-1-antitrypsin; Serpin.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000300015
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Virulence, resistance, and genetic relatedness of Escherichia coli and Klebsiella sp. isolated from mule foals Arq. Bras. Med. Vet. Zootec.
Carneiro,V.C.; Lessa,D.A.B.; Guttmann,P.M.; Magalhaes,H.; Aquino,M.H.C.; Cunha,L.E.R.; Arais,L.R.; Cerqueira,A.M.F..
ABSTRACT Respiratory diseases are common in young horses but little is known about such infections in mule foals. This study aimed to characterize Escherichia coli and Klebsiella sp. isolated from tracheal wash (TW) and fecal samples (FS) of mule foals, with or without cytological evidence of respiratory disease. Strains were analyzed against 13 antimicrobials, for presence of Extended spectrum beta-lactamase (ESBL), and virulence genes. Phylogrouping and Randomic (RAPD)-PCR profiles were used to evaluate their genetic relatedness. E. coli strains from TW and FS showed greatest resistance to tetracycline, while Klebsiella strains were mainly resistant to ampicillin; multidrug resistance and ESBL production were also detected. The blaCTX gene prevailed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Escherichia coli; Klebsiella; Respiratory disease; Virulence; Antimicrobial resistance.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000501073
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