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Rotavirus in adults, Brazil, 2004–2011: G2P[4] dominance and potential impact on vaccination BJID
Luchs,Adriana; Cilli,Audrey; Morillo,Simone Guadagnucci; Carmona,Rita de Cassia Compagnoli; Timenetsky,Maria do Carmo Sampaio Tavares.
Objectives:The aim of this study was to monitor rotavirus (RV) infections in adults >18 years with acute gastroenteritis during 2004–2011 national Brazilian RV surveillance. In addition, to characterize the RV group A (RVA) strains in order to gain insight into the supposed vaccine selective pressure imposed to Brazilian children population.Methods:A total of 2102 convenient fecal specimens were investigated by ELISA, PAGE, and RT-PCR.Results:RV was detected in 203 (9.6%) of 2102 specimens, and showed a marked peak of detection in September. RVA infection was detected in 9.4% (197/2102) and RV group C (RVC) in 0.3% (6/2102). The most frequent genotypes detected in 2004 and 2005 were G9P[8] (38.5%; 5/13) and G1P[8] (54.5%; 6/11), respectively. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rotavirus group A; Rotavirus group C; Adults; Vaccination; Brazil.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100053
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