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Vieira,SL; Favero,A; Berres,J; Freitas,DM; Martinez,JEP; Mayorga,ME; Coneglian,JLB. |
A study was conducted with the objective of evaluating the combined application of tiamulin (TIA) and salinomycin (SAL) in broiler diets fed from 1 to 42 d of age. One thousand and two hundred Cobb x Cobb 500 male broilers were housed in 48 floor pens and fed corn-soybean meal diets containing 66 ppm of SAL combined or not with TIA at 30 or 20 and 20 or 15 ppm, respectively, in the starter (1-21 d) and grower feeds (22-42 d); however, TIA was withdrawn from the feeds 7 days before slaughter. The experimental design was completely randomized with 3 treatments and 16 replicates of 25 birds each. Broilers were weekly evaluated for live performance whereas carcass yield, abdominal fat and commercial cuts were assessed at 42 d using 6 birds randomly taken from... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibiotic; Broiler; Ionophores; Salinomycin; Tiamulin. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2010000100005 |
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Sánchez-Hernández,C; Castañeda-Gómez del Campo,JA; Trejo-Castro,L; Mendoza-Martínez,GD; Gloria-Trujillo,A. |
ABSTRACT Coccidiosis negatively impacts health and productive performance in broilers. Anticoccidial resistance has prompted alternatives to prevent and control this disease. Therefore, the objective of this study was to evaluate a plant feed additive consisting of Acacia concinna containing saponins (Peptasan®) and compare its effectiveness with salinomycin in terms of performance of broilers challenged with Eimeria. In the first experiment, 300 Ross chicks (1 day old) were randomly distributed into a negative (uninfected and untreated), and positive control group (infected and untreated), and three levels of dietary Peptasan® (500, 750 and 1000 ppm). In the second experiment, the same number of chicks were distributed in two control groups (negative and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acacia concinna; Broiler chick; Eimeria; Peptasan®; Salinomycin. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2019000100324 |
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Vedovatto,Marcelo; Diogo,José Mauro da Silva; Beltrame,João Artêmio Marin; D'Oliveira,Marcella Cândia; Silva,Cássio José da; Mendes,Clayton Quirino; Cabral Filho,Sergio Lucio Salomon; Franco,Gumercindo Loriano. |
ABSTRACT The objective was to evaluate the addition of antibiotic growth promoters to free-choice mineral supplement on ingestive behavior, mineral intake, and growth performance of grazing bulls. Sixty Nellore bulls [initial body weight (BW) of 219±17.8 kg and 15±2 months of age] were divided in 12 marandu grass paddocks. The treatments were: mineral supplement (control), mineral supplement + virginiamycin (VIRG), mineral supplement + lasalocid sodium (LASA) and mineral supplement + salinomycin sodium (SALI). Mineral supplements were formulated with target intake of 60 g d−1 and the growth promoters of 75 mg 100 kg−1 of BW. The experimental design was the completely randomized blocks. There was no treatment effect on ingestive behavior or mineral intake;... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Feed additive; Cattle; Ionophore; Lasalocid; Salinomycin; Virginiamycin. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982019000100706 |
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Yu,Z.; Cheng,H.; Zhu,H.; Cao,M.; Lu,C.; Bao,S.; Pan,Y.; Li,Y.. |
Chemotherapy response rates in patients with cholangiocarcinoma remain low, primarily due to the development of drug resistance. Epithelial-mesenchymal transition (EMT) of cancer cells is widely accepted to be important for metastasis and progression, but it has also been linked to the development of chemoresistance. Salinomycin (an antibiotic) has shown some potential as a chemotherapeutic agent as it selectively kills cancer stem cells, and has been hypothesized to block the EMT process. In this study, we investigated whether salinomycin could reverse the chemoresistance of cholangiocarcinoma cells to the chemotherapy drug doxorubicin. We found that combined salinomycin with doxorubicin treatment resulted in a significant decrease in cell viability... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chemotherapy; Cholangiocarcinoma; Drug resistance; Doxorubicin; Salinomycin. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001000607 |
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