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	Provedor de dados J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor Karthikayalu,S (1) Kirubagaran,R (1) Rama,V (1) Venkatesan,R (1) Palavra-chave Cnidarian toxin (1) Cytolysin (1) Sarcophyton trocheliophorum (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2010 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Hemolytic toxin from the soft coral Sarcophyton trocheliophorum: isolation and physiological characterization J. Venom. Anim. Toxins incl. Trop. Dis. Karthikayalu,S; Rama,V; Kirubagaran,R; Venkatesan,R. The unifying characteristic of cnidarians is the production of protein and polypeptide toxins. The present study describes the identification of a hemolytic toxin from the soft coral Sarcophyton trocheliophorum. The crude extract was highly cytotoxic (EC50 = 50 ng/mL) against human erythrocytes. It was also tested for hemolytic activity by the blood agar plate method, resulting in a hemolytic halo of 12 mm with 50 µg of protein. The stability of the venom under different physiological conditions was analyzed. The venom hemolytic activity was augmented by alkaline and neutral pH whereas it was reduced in acidic pH. The activity was stable up to 60º C. The hemolytic activity was completely abolished by the addition of serum and reduced significantly during... Tipo: Info:eu-repo/semantics/article Palavras-chave: Sarcophyton trocheliophorum; Cnidarian toxin; Cytolysin. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000100011 Registros recuperados: 1 Primeira ... 1 ... Última

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