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Bilar,Juliana Miguel; Carvalho-Filho,Roberto José; Mota,Carolina Frade Magalhães Girardin Pimentel; Fucuta,Patricia da Silva; Ferraz,Maria Lucia Cardoso Gomes. |
Approximately 170 million people are infected with hepatitis C, and the sustained virological response rate to treatment with pegylated interferon and ribavirin is 30-50%. In an attempt to improve the chances of cure, boceprevir is being added to therapy, but it is associated with an increased incidence of adverse events. We herein report a case of acute pancreatitis developed during treatment with pegylated interferon, ribavirin and boceprevir. Boceprevir was the most likely cause of drug-associated pancreatitis after the most common causes were ruled out, since this adverse event had not occurred when the patient had previously been exposed to pegylated interferon and ribavirin and there was no recurrence of the episode of pancreatitis when these two... |
Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Hepatitis C; Protease inhibitor; Side effect. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400454 |
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Mahe, Kelig; Ider, Djamila; Massaro, Andrea; Hamed, Oussama; Jurado-ruzafa, Alba; Goncalves, Patricia; Anastasopoulou, Aiketerini; Jadaud, Angelique; Mytilineou, Chryssi; Elleboode, Romain; Ramdane, Zohir; Bacha, Mahmoud; Amara, Rachid; De Pontual, Helene; Ernande, Bruno. |
Otolith shape analysis is an efficient fish stock identification tool. However, most applications used left and right otoliths or only one of them arbitrarily chosen without testing for biases resulting from potential directional bilateral asymmetry (DA) in otolith shape, i.e. a unimodal population-level deviation form bilateral symmetry between right and left otolith shapes. In this study, 560 bogues (Boops boops) were sampled from 11 geographical locations from the Canary Islands to the Aegean Sea and elliptical Fourier descriptors were used to describe their otoliths’ shape. First, a significant otolith DA was observed at the global scale with an average amplitude of 2.77%. However, at the scale of sampling locations, DA was not always significant and... |
Tipo: Text |
Palavras-chave: Boops boops; Elliptical Fourier analysis; Mediterranean Sea; Side effect; Stock identification. |
Ano: 2019 |
URL: https://archimer.ifremer.fr/doc/00468/57967/60418.pdf |
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