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Safety assessment of Spirulina platensis through sprague dawley rats modeling Ciênc. Tecnol. Aliment.
BASHIR,Shahid; SHARIF,Mian Kamran; JAVED,Muhammad Sameem; AMJAD,Adnan; KHAN,Ammar Ahmad; SHAH,Faiz-ul-Hassan; KHALIL,Anees Ahmad.
Abstract Health safety of spirulina (Spirulina platensis) for food application was evaluated through hematology and histopathology of liver, spleen and kidney in Sprague Dawley rats fed on three isoproteic diets maintained to 10% protein for forty five days. Three groups of rats were maintained as control diet casein (R-C); diet containing crude spirulina (R-S) and diet containing purified spirulina protein (R-SPI). Hematological profile of the rats group fed on spirulina diets showed no significant increase in white blood cells (WBCs), while there was decreasing trend in the levels of neutrophils (60.46 ± 2.60%) and lymphocytes (33.53 ± 1.06%) in rats that were fed on spirulina diet (R-S) than the other tested experimental diet group. Histopathological...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Spirulina; Spirulina protein isolates; Hematology; Histopathology; Algal toxicology.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000200376
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