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The polymorphisms of genes associated with the profile of fatty acids of sheep Arq. Bras. Med. Vet. Zootec.
Esteves,C.; Livramento,K.G.; Paiva,L.V.; Peconick,A.P.; Garcia,I.F.F.; Garbossa,C.A.P.; Faria,P.B..
ABSTRACT The present study aimed to evaluate the occurrence of polymorphisms in Diacylglycerol acyltransferase (DGTA-1 and 2), Fatty acid synthase (FASN), Stearoyl-CoA desaturase (SCD) genes and the Thioesterase domain of FASN (TE-FASN) gene that may be related to the lipid profile. In the experiment, a total of 84 sheep from different genetic groups were used. For the evaluation of the polymorphism of the genes, PCR-Single Strand Conformation Polymorphism (SSCP) technique and subsequent sequencing were used. In DGAT-2 gene, four genotypes were identified with the presence of 6 polymorphisms, with two (c.229T> C; c.255T> C) that resulted into the exchange of phenylalanine by leucine. In FASN gene, two genotypes were identified. In TE-FASN gene, three...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diacylglycerol acyltransferase; Fatty acid synthase; Stearoyl-CoA desaturase.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100303
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