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Registros recuperados: 36
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Imprime registro no formato completo
A randomized, pilot trial comparing full versus escalating dose regimens for the desensitization of AIDS patients allergic to sulfonamides BJID
Straatmann,Andrea; Bahia,Fabianna; Pedral-Sampaio,Diana; Brites,Carlos.
Sulfonamides are drugs extensively used in the management of AIDS patients. However, the use of sulfonamides is often associated with the development of allergic reactions, provoking the substitution of the drug (by another that may be less effective); alternatively attempts are made to desensitize the patient. OBJECTIVE: Compare two drug regimens (full vs. escalating doses) for the oral desensitization of AIDS patients allergic to sulfonamides. MATERIAL AND METHODS: AIDS patients with previous allergic reactions to sulfonamides and requiring prophylaxis against Pneumocistis carinii, central nervous system toxoplasmosis and diarrhea caused by Isospora belli were randomly assigned to a group receiving a routine dose of cothrimoxazole, or another that...
Tipo: Info:eu-repo/semantics/article Palavras-chave: AIDS; Allergy; Sulfonamides; Oral desensitization.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600002
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2-Phenitidine derivatives as suitable inhibitors of butyrylcholinesterase BJPS
Abbasi,Muhammad Athar; Aziz-ur-Rehman,; Qureshi,Muhammad Zahid; Khan,Farhan Mehmood; Khan,Khalid Mohmmed; Ashraf,Muhammad; Afzal,Iftikhar.
This manuscript reports the synthesis of a series of N-substituted derivatives of 2-phenitidine. First, the reaction of 2-phenitidine (1) with benzene sulfonyl chloride (2) yielded N-(2-ethoxyphenyl) benzenesulfonamide (3), which further on treatment with sodium hydride and alkyl halides (4a-g) furnished into new sulfonamides (5a-g). Second, the phenitidine reacted with benzoyl chloride (6) and acetyl chloride (8) to yield the reported N-benzoyl phenitidine (7) and N-acetyl phenitidine (9), respectively. These derivatives were characterized by infrared spectroscopy, ¹H-NMR, and EI-MS, and then screened against acetylcholinesterase, butylcholinesterase, and lipoxygenase enzyme, and were found to be potent inhibitors of butyrylcholinesterase alone.
Tipo: Info:eu-repo/semantics/article Palavras-chave: 2-Phenitidine/inhibitor activity; Sulfonamides; Acetamide; Benzamide; Butyrylcholinesterase.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000100014
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N-(1,4-Dihydro-pyrimidin-2-yl)-benzenesulfonamide eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A.; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: C~10~H~9~N~3~O~2~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/188/
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4-Amino-benzenesulfonamide 1-Morpholin-4-yl-ethanone solvate eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A.; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: (C~6~H~11~NO~2~).(C~6~H~8~N~2~O~2~S); Organic; Strctural systematics; Sulfonamides; Sulfur drugs.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/192/
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N-[4-(3-Methyl-1H-pyridin-2-ylidene sulfamoyl)-phenyl]-acetamide eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A.; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: C~14~H~15~N~3~O~3~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/179/
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4-Amino-N-Pyridin-2-yl-benzenesulfonamide with Formic acid butyl ester eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A.; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: C~16~H~20~N~3~O~4~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/196/
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4-Amino-N-(3-methyl-1H-pyridin-2-ylidene)-benzenesulfonamide eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A.; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: C~12~H~13~N~3~O~2~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/178/
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N-(5-Chloro-pyridin-2-yl)-benzenesulfonamide eCrystals
Threlfall, Terry L; Coles, Simon J.; Ward, Suzanna C; Hursthouse, Michael B..
Tipo: Crystal Structure Data Holding Palavras-chave: C~11~H~9~ClN~2~O~2~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 1999 URL: http://ecrystals.chem.soton.ac.uk/172/
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4-Methyl-N-(4-methyl-1H-pyridin-2-ylidene)-benzenesulfonamide eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A.; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: C~13~H~14~N~2~O~2~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/193/
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N-(3-Methyl-1H-pyridin-2-ylidene)-benzenesulfonamide eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A.; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: C~12~H~12~N~2~O~2~S; Organic; Structural systematics; Sulfonamides; Sulfer drugs.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/197/
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N-(5-Chloro-pyridin-2-yl)-4-methyl-benzenesulfonamide eCrystals
Threlfall, Terry L; Coles, Simon J.; Ward, Suzanna C; Hursthouse, Michael B..
Tipo: Crystal Structure Data Holding Palavras-chave: C~12~H~11~ClN~2~O~2~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 1999 URL: http://ecrystals.chem.soton.ac.uk/176/
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4-Methyl-N-(5-methyl-3H-[1,3,4]thiadiazol-2-ylidene)-benzenesulfonamide eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A.; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: C~10~H~11~N~3~O~2~S~2~; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/195/
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N-[4-(1,4-Dihhydro-pyrazin-2-ylsulfamoyl]-acetamide eCrystals
Threlfall, Terry L; Coles, Simon J.; Ward, Suzanna C; Hursthouse, Michael B..
Tipo: Crystal Structure Data Holding Palavras-chave: C~12~H~12~N~4~O~3~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 1999 URL: http://ecrystals.chem.soton.ac.uk/168/
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4-Amino-N-(1H-pyridin-2-ylidene)-benzenesulfonamide and tetrahydro-furan solvate eCrystals
Threlfall, Terry L; Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A..
Tipo: Crystal Structure Data Holding Palavras-chave: (C~11~H~11~N~3~O~2~S).(C~4~H~8~O); Organic; Structural systematics; Sulfonamides; Sulfur drugs; Co-crystal.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/183/
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N-[4-(1,4-Dihydro-pyrazin-2-ylsulfamoyl)-phenyl]-acetamide eCrystals
Threlfall, Terry L; Coles, Simon J.; Ward, Suzanna C; Hursthouse, Michael B..
Tipo: Crystal Structure Data Holding Palavras-chave: C~12~H~12~N~4~O~3~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 1999 URL: http://ecrystals.chem.soton.ac.uk/167/
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Imprime registro no formato completo
N-(4-Methyl-1H-pyridin-2-ylidene)-benzenesulfonamide eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A.; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: C~12~H~12~N~2~O~2~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/177/
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Imprime registro no formato completo
4-Amino-benzenesulfonamide eCrystals
Threlfall, Terry L; Coles, Simon J.; Ward, Suzanna C; Hursthouse, Michael B..
Tipo: Crystal Structure Data Holding Palavras-chave: C~6~H~8~N~2~O~2~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 1999 URL: http://ecrystals.chem.soton.ac.uk/166/
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4-Methyl-N-pyridin-2-yl-benzamide eCrystals
Coles, Simon J.; Threlfall, Terry L; Mayer, Thomas A.; Hursthouse, Michael B..
Tipo: Crystal Structure Data Holding Palavras-chave: C~13~H~12~N~2~O; Organic; Structural systematic; Sulfonamides; Sulfur drugs.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/201/
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Imprime registro no formato completo
N-(5-Methyl-pyridin-2-yl)-benzenesulfonamide eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Ward, Suzanna C; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: C~12~H~12~N~2~O~2~S; Organic; Structural systematics; Sulfonamides; Sulfur drugs.
Ano: 1999 URL: http://ecrystals.chem.soton.ac.uk/163/
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Imprime registro no formato completo
4-Amino-N-(4-methyl-1H-pyridin-2-ylidene)-benzenesulfonamide eCrystals
Coles, Simon J.; Hursthouse, Michael B.; Mayer, Thomas A.; Threlfall, Terry L.
Tipo: Crystal Structure Data Holding Palavras-chave: C~12~H~13~N~3~O~2~S; Organic; Structural systematics; Sulfur drugs; Sulfonamides.
Ano: 2000 URL: http://ecrystals.chem.soton.ac.uk/180/
Registros recuperados: 36
Primeira ... 12 ... Última
 

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