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	Provedor de dados BJPS (3) Autor Auda,Sayed Hassan (1) Chabukswar,Aniruddha Rajaram (1) Ibrahim,Mohamed Abbas (1) Jadhav,Vinayak Narhari (1) Jagdale,Swati Changdeo (1) Kassem,Mohamed Gabr (1) Kuchekar,Bhanudas Shankar (1) Mahrous,Gamal Mohamed (1) Ramírez,Daniel García (1) Robles,Leopoldo Villafuerte (1) Mais... Palavra-chave Superdisintegrants (3) Amoxicillin (1) Clopidogrel/orally disintegrating tablets (1) Excipients/functionality (1) Fast-dissolving tablets (1) Magnesium stearate (1) Nifedipine/dissolution (1) Orally disintegrating tablets/evaluation (1) Orally disintegrating tablets/formulation (1) Polyplasdones XL/functionality (1) Polyplasdones XL10/functionality (1) Tablets/compactibility (1) Tablets/disintegration time (1) Tablets/powder flow (1) Β-ciclodextrin/complexation (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2016 (1) 2015 (1) 2012 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Contrasting the crospovidones functionality as excipients for direct compression BJPS Ramírez,Daniel García; Robles,Leopoldo Villafuerte. Specific values of technological properties of excipients allow the establishment of numerical parameters to define and compare their functionality. This study investigates the functionality of Polyplasdones XL and XL10. Parameters studied included tablet disintegration profiles, compactibility profiles and powder flow. The results allowed the establishment of quantitative surrogate functionalities of technological performance, such as absolute number, and as a value relative to the known microcrystalline cellulose type 102. Moreover, the establishment of an explicit functionality to improve the technological performance of two diluents and a model drug was investigated, as was setting up of these functionalities, as quantitative values, to determine the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Excipients/functionality; Polyplasdones XL/functionality; Polyplasdones XL10/functionality; Tablets/compactibility; Tablets/disintegration time; Tablets/powder flow; Amoxicillin; Magnesium stearate; Superdisintegrants. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100155 Formulation and evaluation of orally disintegrating clopidogrel tablets BJPS Mahrous,Gamal Mohamed; Kassem,Mohamed Gabr; Ibrahim,Mohamed Abbas; Auda,Sayed Hassan. ABSTRACT Recent advances in drug delivery systems have aimed to achieve better patient compliance. One of these advances is the formulation of orally disintegrating tablets (ODTs) that dissolve instantaneously, releasing drugs within a few seconds without the need of water. The main objective of this paper was to prepare and develop ODTs of clopidogrel. The ODTs were prepared by direct compression. The effect of three superdisintegrants, namely crospovidone, croscarmellose sodium, and sodium starch glycolate, using three different disintegration times on the dissolution rate was investigated. The prepared tablets were evaluated for hardness, friability, disintegration time and in vitro drug release. Furthermore, the interaction of clopidogrel with the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Clopidogrel/orally disintegrating tablets; Superdisintegrants; Orally disintegrating tablets/formulation; Orally disintegrating tablets/evaluation. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000200309 Solubility enhancement, physicochemical characterization and formulation of fast-dissolving tablet of nifedipine-betacyclodextrin complexes BJPS Jagdale,Swati Changdeo; Jadhav,Vinayak Narhari; Chabukswar,Aniruddha Rajaram; Kuchekar,Bhanudas Shankar. The main objective of the study was to enhance the dissolution of nifedipine, a poorly water soluble drug by betacyclodextrin complexation and to study the effect of the preparation method on the in vitro dissolution profile. The stoichiometric ratio determined by phase solubility analysis for inclusion complexation of nifedipine with β-cyclodextrin was 1:1. Binary complex was prepared by different methods and was further characterized using XRD, DSC and FT-IR. A saturation solubility study was carried out to evaluate the increase in solubility of nifedipine. The optimized complex was formulated into fast-dissolving tablets by using the superdisintegrants Doshion P544, pregelatinized starch, crospovidone, sodium starch glycolate and croscarmellose sodium... Tipo: Info:eu-repo/semantics/article Palavras-chave: Fast-dissolving tablets; Nifedipine/dissolution; Β-ciclodextrin/complexation; Superdisintegrants. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000100015 Registros recuperados: 3 Primeira ... 1 ... Última

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