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Phenolic content and antioxidant activity of parts of Passiflora edulis as a function of plant developmental stage Acta Botanica
Guimarães,Sarah F.; Lima,Inorbert M.; Modolo,Luzia V..
ABSTRACT Passiflora edulis Sims var. flavicarpa O. Deg. (Yellow-passion fruit) is the native plant species most used by juice industries in Brazil while its leaf extracts are widely employed in folk medicine. This study evaluated the phenolic content of leaves, roots, fruit shells and pulp of plants of P. edulis in juvenile, flowering and fruiting stages. The extent of scavenging and/or degradation of reactive nitrogen and oxygen species by plant extracts was also investigated. Leaves were the organs that most accumulated phenolics/flavonoids, regardless of plant developmental stage. Leaf extracts efficiently scavenged DPPH by up to 67 % while root and fruit shell extracts effectively captured up to 80 % O2 -. Maximum activity of catalase (51.6 mmol H2O2...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant enzymes; DPPH; Flavonoids; Passion fruit; Secondary metabolism; Superoxide anion.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-33062020000100074
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Polyphenols and Red Wine as Antioxidants against Peroxynitrite and other Oxidants Biol. Res.
VALDEZ,LAURA B; ÁLVAREZ,SILVIA; ZAOBORNYJ,TAMARA; BOVERIS,ALBERTO.
The antioxidant capacity of polyphenols (+)-catechin, (-)-epicatechin and myricetin, and of different types of red wines (Cabernet Sauvignon, Malbec and blended wine) was evaluated by three assays. (a) NADH oxidation by peroxynitrite (ONOO-): the ONOO- scavenging activity was higher for myricetin (IC50=35 µM) than for (+)-catechin (IC50=275 µM) and (-)-epicatechin (IC50=313 µM). (b) Peroxynitrite initiated chemiluminescence in rat liver homogenate: (-)-epicatechin (IC50=7.0 µM) and (+)-catechin (IC50=13 µM) were more potent than myricetin (IC50=20 µM) in inhibiting the chemiluminescence signal. (c) Lucigenin chemiluminescence in aortic rings: (-)-epicatechin (IC50=15 µM) and (+)-catechin (IC50=18 µM) showed higher antioxidant capacity than myricetin...
Tipo: Journal article Palavras-chave: Antioxidant capacity; Peroxynitrite; Polyphenols; Red wines; Superoxide anion.
Ano: 2004 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000200014
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The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2 BJMBR
Maioli,N.A.; Zarpelon,A.C.; Mizokami,S.S.; Calixto-Campos,C.; Guazelli,C.F.S.; Hohmann,M.S.N.; Pinho-Ribeiro,F.A.; Carvalho,T.T.; Manchope,M.F.; Ferraz,C.R.; Casagrande,R.; Verri Jr,W.A..
It is currently accepted that superoxide anion (O2•−) is an important mediator in pain and inflammation. The role of superoxide anion in pain and inflammation has been mainly determined indirectly by modulating its production and inactivation. Direct evidence using potassium superoxide (KO2), a superoxide anion donor, demonstrated that it induced thermal hyperalgesia, as assessed by the Hargreaves method. However, it remains to be determined whether KO2 is capable of inducing other inflammatory and nociceptive responses attributed to superoxide anion. Therefore, in the present study, we investigated the nociceptive and inflammatory effects of KO2. The KO2-induced inflammatory responses evaluated in mice were: mechanical hyperalgesia (electronic version of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Superoxide anion; Potassium superoxide; Pain; Inflammation; Oxidative stress.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000400321
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