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	Provedor de dados J. Venom. Anim. Toxins (1) J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor DORCE,V. A. C. (1) Gawade,S. P. (1) LEBRUN,I. (1) MARUO,V. M. (1) Reddy,C. M. (1) Palavra-chave Learning and memory (2) T-maze (2) Elevated plus-maze (1) Forced swim test (1) Open-field (1) Passive avoidance (1) Photooxidized Echis carinatus venom product (1) Scorpion neurotoxin (1) TS-8F toxin (1) Tityus serrulatus (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2006 (1) 2002 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última EFFECTS OF SCORPION Tityus serrulatus VENOM TOXIN TS-8F ON RAT LEARNING AND MEMORY J. Venom. Anim. Toxins MARUO,V. M.; LEBRUN,I.; DORCE,V. A. C.. Scorpion venom neurotoxins are responsible for toxicity and pharmacological effects. They are active in sodium and potassium channels leading to an increase in the release of neurotransmitters, such as glutamate. Glutamate is found in large quantities in the hippocampus (HPC) and is involved in the long-term potentiation (LTP) induction. The HPC is known to be related to certain kinds of memory. The aim of this study is to evaluate the effects of Tityus serrulatus TS-8F toxin on rat behavior with emphasis on learning and memory. We analyzed the effects of different doses of TS-8F on rat behavior in home cages, open-field (habituation), inhibitory avoidance, T-maze, and hippocampus morphology. In the first two experiments, 0.05µg/animal dose of TS-8F did... Tipo: Info:eu-repo/semantics/article Palavras-chave: Learning and memory; Scorpion neurotoxin; Tityus serrulatus; T-maze; Open-field; Passive avoidance; TS-8F toxin. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000100007 Evaluation of the effects of photooxidized Echis carinatus venom on learning, memory and stress J. Venom. Anim. Toxins incl. Trop. Dis. Reddy,C. M.; Gawade,S. P.. Snake venoms are a mixture of complex proteins, which have many physical and pharmacological properties. Photochemical detoxification has been suggested to generate photooxidized Echis carinatus venom product (POECVP). Antigenically-active photooxidized species of Echis carinatus venom could be obtained by exposing the venom to ultraviolet radiation (UVR) in the presence of methylene blue. The aim of the present study was to evaluate the effects of POECVP on learning, memory and stress in rats. Detoxification of the photooxidized venom was evident since the POECVP-treated group had longer survival time than the group of mice treated with Echis carinatus venom product (ECVP) following intraperitoneal and intracerebral injections. Photooxidized Echis... Tipo: Info:eu-repo/semantics/article Palavras-chave: Learning and memory; Photooxidized Echis carinatus venom product; T-maze; Forced swim test; Elevated plus-maze. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000400010 Registros recuperados: 2 Primeira ... 1 ... Última

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