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| Fanpu,Ji; Zhang,Shu; Huang,Na; Deng,Hong; Li,Zongfang. |
| Patients with hepatitis C virus-related decompensated cirrhosis can benefit frominterferonbased antiviral therapy, but the common complication of cytopenia is a contraindication for this treatment. Splenectomy prior to interferon therapy may alleviate this problem. To investigate whether splenectomy improves the efficacy of antiviral therapy, 13 interferonnaïve hepatitis C virus decompensated cirrhotic patients underwent splenectomy between January 2008 and January 2011, followed 1-3 months later by an interferon-based therapeutic regimen (pegylated/standard interferon-α combined with ribavirin for 48 weeks). Ten (76.9%) of the patients developed postoperative complications, which included minor portal vein thrombosis (2/13, 15.4%) and transient ascites... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Hepatitis C virus; Thrombocytopenia; Splenectomy; Antiviral therapy. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500014 |
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| Weng,Yali; Chen,Nian; Han,Yaping; Xing,Yiping; Li,Jun. |
| Severe fever with thrombocytopenia syndrome (SFTS) associated with severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging infectious disease. 12 patients with severe fever with thrombocytopenia syndrome in our study were presented mainly with fever and severe malaise. The clinical manifestations typically became worse on the 6th or 7th day. The average fever time is 9.11 ± 1.54 days. Most of them had multiorgan dysfunction, and part of them had hemophagocytic lymphohistiocytosis histiocytosis (HLH). The characteristic laboratory findings in the early stage were the drop of white blood cells (WBC), platelets (PLT) and serum Ca++, while increase of aspartate amino transferase (AST), creatine kinase (CK), and lactate dehydrogenase (LDH).... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Thrombocytopenia; Bunyaviridae infection; Clinical features; Laboratory characteristics. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100088 |
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| Rocha,Jaime Luís Lopes; Kondo,William; Baptista,Maria Inêz Domingues Kuchiki; Cunha,Clovis Arns da; Martins,Luzilma Terezinha Flenik. |
| Vancomycin has been used with increased frequency during the past 15 years and the most common toxicity with this drug is the "red man syndrome". Other adverse effects include neutropenia, fever, phlebitis, nephrotoxicity, ototoxicity, thrombocytopenia, interstitial nephritis, lacrimation, linear IgA bullous dermatosis, necrotizing cutaneous vasculitis and toxic epidermal necrolysis. Only two cases of vancomycin-induced Stevens-Johnson syndrome and one case of pancytopenia have been reported in the medical literature. The treatment for both situations is based on cessation of the vancomycin therapy; in cases of Stevens-Johnson syndrome, antihistamine and/or steroid agents can be used. This article reports a case of pancytopenia and a case of erythema major... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vancomycin; Stevens-Johnson; Pancytopenia; Reactions; Thrombocytopenia. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000400007 |
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| Su,Hung-Yuan; Huang,Shih-Wei; Mao,Yan-Chiao; Liu,Ming-Wen; Lee,Kuo-Hsin; Lai,Pei-Fang; Tsai,Ming-Jen. |
| Abstract Background: There are 6 species of venomous snakes in Taiwan. Two of them, Deinagkistrodon acutus (D. acutus) and Daboia siamensis (D. siamensis), can cause significant coagulopathy. However, a significant proportion of patients with snakebites cannot identify the correct snake species after envenomation, which hampers the application of antivenom. Hence, the differential diagnosis between the two snakebites by clinical presentations is important. This study aims to compare their clinical and laboratory features for the purpose of differential diagnosis between the two snakebites. Methods: We retrospectively reviewed the medical records of patients who arrived at the emergency department due to D. acutus or D. siamensis envenomation, between... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coagulopathy; Deinagkistrodon acutus; Daboia siamensis; Snakebite; Thrombocytopenia. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100333 |
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| Abdallah,N; Abdel Aziz,HK; Hamed,NA; Gamal,M. |
| Hepatitis C virus (HCV) patients commonly have low platelet counts; however, the exact role of HCV infection in thrombocytopenia is unknown. This work aimed to study the serum levels of interleukins (IL) 10 and 12 in patients with mild and moderate thrombocytopenia associated with chronic hepatitis C infection. Our study included 15 patients with chronic HCV infection and newly diagnosed isolated autoimmune thrombocytopenia (Group I) and 15 patients with chronic HCV infection and normal platelet count as controls (Group II). All patients were examined for personal history and clinical aspects, complete blood count, bone marrow aspiration, liver function tests, HCV antibody assay by ELISA and polymerase chain reaction (PCR), abdominal ultrasound,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Interleukin-10; Interleukin-12; Thrombocytopenia; Hepatitis C activity. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000300012 |
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| Cheng,Chin-Lung; Mao,Yan-Chiao; Liu,Po-Yu; Chiang,Liao-Chun; Liao,Shu-Chen; Yang,Chen-Chang. |
| Abstract Background Deinagkistrodon acutus envenomation is associated with severe hematological and wound complications but is rarely described. Case presentation Herein, we report three cases of victims bitten by D. acutus and indicate that rapid-onset severe coagulopathy and thrombocytopenia are distinct features of D. acutus snakebite, which are not observed in other crotaline snakebites (i.e., Trimeresurus stejnegeri and Protobothrops mucrosquamatus) in Taiwan. The toxic effects could occur as early as 2 to 3 h following D. acutus envenomation and persist if the administration of specific antivenom is delayed or even not commenced. Based on our findings, 2 to 4 vials of specific antivenom as the first dose should be administered to victims and... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Coagulopathy; Thrombocytopenia; Envenomation; Deinagkistrodon acutus; Snakebite. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100504 |
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| Baltazar, Fabio Navarro; Sena, Alex Lafarti de; Augusto, Cecília F. B.; Chemin, Andréa; Bearl, Carla Alice; Quinzani, Marcelo. |
| Immune-mediated thrombocytopenia, platelet destruction mediated by humoral and cellular responses, is frequently observed in dogs, especially in middle-age females of spaniels and Doberman breeds. The first line therapy involves the administration of corticosteroids in immunosuppressive doses and, in refractory cases, the pharmacological combination with other immunomodulatory agents seems often necessary. This case report describes the successful combination of vincristine sulfate to glucocorticoids (Dexamethasone) during the hospitalization of a dog with primary immune-mediated thrombocytopenia and related spontaneous bleeding, and discusses the therapeutic modalities in the literature. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Thrombocytopenia; Autoimmunity; Dogs trombocitopenia; Autoimunidade; Cães. |
| Ano: 2015 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/25560 |
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