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	Provedor de dados BJPS (2) Autor Aguiar Júnior,Nelson dos Reis (1) Bagatin,Edileia (1) Bentley,Maria Vitória Lopes Badra (1) Campos,Patrícia Maria Berardo Gonçalves Maia (1) Fonseca,Maria José Vieira (1) Georgetti,Sandra Regina (1) Gianeti,Mirela Donato (1) Gonçalves,Erika Maria Berardo (1) Vicentini,Fabiana Testa Moura de Carvalho (1) Wagemaker,Tais Aleriana Lucon (1) Mais... Palavra-chave Topical formulations/analysis (2) Chemical peeling (1) DPPH• (1) High performance liquid chromatography (1) Quercetin/extraction (1) Quercetin/liberation (1) Quercetin/quantification (1) Skin penetration in vitro/study (1) TretinoinTretinoin/skin penetration/in vitro study (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2015 (1) 2009 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Assessment of in vitro methodologies to determine topical and transdermal delivery of the flavonoid quercetin BJPS Vicentini,Fabiana Testa Moura de Carvalho; Georgetti,Sandra Regina; Bentley,Maria Vitória Lopes Badra; Fonseca,Maria José Vieira. To be effective against the oxidative damages induced by UVB irradiation in the skin, the drug needs to release from the formulation in which it was incorporated and reach the skin layers where the ROS are generated. Thus, it is very important the development of a robust and sensitive methodology to extract and quantify in different skin layers the antioxidant agent delivered from topical formulations. Therefore, in the present work suitable methods to extract and quantify quercetin in skin samples and receptor phase after in vitro penetration studies were developed. The results demonstrated that the recovery from two different layers of skin, the SC and [E+D], using two different methods of quantification (DPPH• assay and HPLC, respectively), was 93.8 %... Tipo: Info:eu-repo/semantics/article Palavras-chave: Topical formulations/analysis; Quercetin/quantification; Quercetin/extraction; Quercetin/liberation; Skin penetration in vitro/study; High performance liquid chromatography; DPPH•. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000200022 Tretinoin-based formulations - influence of concentration and vehicles on skin penetration BJPS Bagatin,Edileia; Wagemaker,Tais Aleriana Lucon; Aguiar Júnior,Nelson dos Reis; Gianeti,Mirela Donato; Gonçalves,Erika Maria Berardo; Campos,Patrícia Maria Berardo Gonçalves Maia. Tretinoin is used in the management of acne and it is part of a gold standard treatment for photoaging. It has also been reported as an agent for superficial chemical peeling in highly concentrated formulations with few considerations about skin penetration. The aim of this study was to evaluate the influence of drug concentration and vehicles currently used on skin penetration of tretinoin. In vitro permeation tests were carried out using Franz diffusion cells fitted with porcine ear skin and 10% aqueous methanol in the receptor compartment. Formulations studied, cream or hydroalcoholic dispersion, containing 0.25%, 1% and 5% of tretinoin were placed in the donor compartment for six hours. Tretinoin concentration in skin layers was measured by high... Tipo: Info:eu-repo/semantics/article Palavras-chave: TretinoinTretinoin/skin penetration/in vitro study; Chemical peeling; Topical formulations/analysis. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100085 Registros recuperados: 2 Primeira ... 1 ... Última

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