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Registros recuperados: 141
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Effects of culture filtrates of endophytic fungi obtained from Piper aduncum L. on the growth of Mycobacterium tuberculosis Electron. J. Biotechnol.
Lima,Alita Moura de; Salem,Júlia Ignez; Souza,João Vicente Braga de; Cortez,Ana Claudia Alves; Carvalho,Clarice Maia; Chaves,Francisco Célio Maia; Veiga Junior,Valdir Florêncio da.
Substances that inhibit the growth of Mycobacterium tuberculosis could potentially be used as antibiotics. These substances could also be added to test culture media to improve the speed of tuberculosis diagnosis. The aim of this work was to investigate the influence of culture filtrates of endophytic fungi isolated from P. aduncum L. on the growth of M. tuberculosis. To achieve this objective, the following methodology was used: a) endophytic fungi were isolated from the leaves and stems of P. aduncum L.; b) the isolated fungi were submitted to submerged bioprocessing; c) culture filtrates from the bioprocess were assayed to evaluate their effect on the growth of M. tuberculosis. We isolated 315 fungal types, which represented 85 morphologies, from...
Tipo: Journal article Palavras-chave: Antagonism; Stimulation growth; Tuberculosis.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582011000400008
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A two-step strategy for the complementation of M: tuberculosis mutants Genet. Mol. Biol.
Movahedzadeh,Farahnaz; Frita,Rosangela; Gutka,Hiten J..
The sequence of Mycobacterium tuberculosis, completed in 1998, facilitated both the development of genomic tools, and the creation of a number of mycobacterial mutants. These mutants have a wide range of phenotypes, from attenuated to hypervirulent strains. These phenotypes must be confirmed, to rule out possible secondary mutations that may arise during the generation of mutant strains. This may occur during the amplification of target genes or during the generation of the mutation, thus constructing a complementation strain, which expresses the wild-type copy of the gene in the mutant strain, becomes necessary. In this study we have introduced a two-step strategy to construct complementation strains using the Ag85 promoter. We have constitutively...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; Mutagenesis; Constitutive expression; Complementation.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000200020
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Tuberculosis Intestinal Secundaria: Hallazgos Morfológicos en un Caso con Desenlace Fatal International Journal of Morphology
Tapia E,Oscar.
La tuberculosis gastrointestinal (TB GI) representa el 3-5% de todos los casos de TB extrapulmonar, reportándose que hasta el 20% de los sujetos con TB pulmonar presentan manifestaciones extra-pulmonares que incluyen enfermedades intra-abdominales, sin embargo, se desconoce la real incidencia del compromiso intestinal. La región ileocecal representa el sitio anatómico más frecuentemente afectado (85-90%), siendo actualmente la colonoscopía la herramienta diagnóstica de mayor utilidad. Se presentan los hallazgos morfológicos del examen post-mortem de una paciente en estudio por baja de peso y masa en región cecal. La necropsia realizada en la Unidad de Anatomía Patológica del Hospital Hernán Henríquez Aravena de Temuco concluyó una TB pulmonar bilateral con...
Tipo: Journal article Palavras-chave: Tuberculosis; Gastrointestinal; Tuberculosis intestinal.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100061
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Pericarditis Constrictiva Tuberculosa: Reporte de un Caso y Revisión de la Literatura International Journal of Morphology
Tapia E,Oscar.
La pericarditis tuberculosa (PT) representa una rara manifestación extrapulmonar de tuberculosis (TBC), que se encuentra en aproximadamente el 1% de las autopsias por TBC y 1-2% de casos de TBC pulmonar, estando su presentación estrechamente asociado con la infección por VIH. El compromiso pericárdico ocurre habitualmente por diseminación linfática retrógrada o diseminación hematógena desde un foco pulmonar primario, pudiendo clínicamente manifestarse como derrame pericárdico, pericarditis constrictiva o un patrón mixto. El presente trabajo, describe los hallazgos clínicos y morfológicos de un caso de PT en un sujeto inmunocompetente de 78 años, con diagnóstico de PT constrictiva efectuado en el Hospital Hernán Henríquez Aravena de Temuco.
Tipo: Journal article Palavras-chave: Pericarditis; Tuberculosis; Tuberculous pericarditis.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200056
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Morphometric Analysis of Granulomas Induced by Mycobacterium bovis Suggests an Influence of IFN-Gamma on the Generation and Modulation upon Granulomatous Inflammatory Response in the Different Tissues International Journal of Morphology
Azevedo Duarte,Tonya; Almeida Barbosa Jr.,Aryon de; Arruda,Sergio.
There is evidence in both human and experimental infection caused by Mycobacterium tuberculosis, that immunologic factors influence susceptibility to infection and the progress of the disease. The present study aims to evaluate the role of IFN- g upon inflammatory granulomatous response against M. bovis. To pursue that, C57BL/6 mice lacking the genes for synthesis of IFN- g (IFN- g-/-) and their wild-type counterparts (IFN- g+/+) were intravenously inoculated with M. bovis. The ability of M. bovis to survive and replicate in the liver and lungs was evaluated by counting colony-forming unit (CFU). The histopathological features of granulomatous inflammatory response in the liver and lungs were analyzed during the infection by M. bovis. Granuloma parameters...
Tipo: Journal article Palavras-chave: Morphometry; Mycobacterium; Tuberculosis; IFN-g; Granuloma.
Ano: 2005 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000400006
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Respuesta a la prueba tuberculínica comparativa en ovinos de establecimientos mixtos de la región norte de la provincia de La Pampa InVet
Castillo,M.; Gómez,M.B.; Cerutti,D.A.; Meglia,G.E..
La situación de la tuberculosis bovina se determina a través de la técnica diagnóstica intradérmica en los rebaños. Se ha aislado el agente causal y comprobado casos en ovinos, cuya producción en Argentina se orienta a un sistema más intensificado, con destino interno y externo. En el marco del Plan Nacional de Control y Erradicación de la Tuberculosis bovina, es necesario incorporar a los ovinos, puesto que ambas especies son huéspedes del mismo patógeno, actuando como reservorios y/o diseminadores de la infección para especies de interés productivo y el hombre. El diagnóstico en ovinos se realiza a través de la prueba tuberculínica comparativa, actuando a su vez, de screening para infecciones como pseudotuberculosis y paratuberculosis. En La Pampa, no...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; Prueba tuberculínica; Ovinos; Norte de La Pampa.
Ano: 2017 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-34982017000200001
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Comparación de técnicas diagnósticas de tuberculosis porcina en dos establecimientos de cría confinada en Argentina InVet
Magnano,G.G.; Schneider,M.O.; Urbani,C.E.; Ambrogi,A.; Zapata,L.; Jorge,M.C..
El diagnóstico de tuberculosis en animales vivos se realiza casi exclusivamente mediante la prueba intradérmica tuberculínica (IDR), aunque en los porcinos son escasos los reportes de resultados utilizando dicha técnica. El objetivo de este trabajo fue comparar resultados obtenidos realizando la IDR en porcinos con hallazgos patológicos y microbiológicos. Se tuberculinizaron 307 hembras con DPP aviar y DPP bovino. Del total, 171 se inspeccionaron a la faena tomando muestras para exámenes bacteriológicos e histopatológicos. Los resultados de la IDR fueron: 14.4% (44) positivos a DPP aviar, 1.9% (6) a DPP bovino, 3.9% (12) a ambos DPP y 79.8% (245) negativos. Cuatro muestras fueron positivas al cultivo, tipificándose como Mycobacterium bovis, M. avium, M....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diagnóstico; Porcinos; Tuberculosis.
Ano: 2010 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-34982010000100004
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Repetición de la prueba de intradermorreacción tuberculínica en bovinos naturalmente infectados y modificaciones del pliegue anocaudal InVet
Schneider,M; Magnano,G; Bergamo,E; Urbani,C; Herrera,P; Quiroga,A; Macías,A; Meikle,V; Cataldi,A; Giraudo,J.
El presente trabajo tuvo como objetivo evaluar la repetición de la prueba de intradermorreacción (IDR) en bovinos y comprobar la evolución en el tamaño y consistencia que se producen en el pliegue anocaudal en los días sucesivos a la aplicación del derivado proteico purificado (PPD). Se utilizaron 14 vaquillonas infectadas naturalmente con Mycobacterium bovis a las cuales se les repitió en tres oportunidades la IDR en el pliegue anocaudal analizando como se modificaban diariamente las características físicas del pliegue. El 92.2% de los animales fueron positivos en las tres repeticiones y se observó disminución en el tamaño de la reacción en las sucesivas repeticiones. Esto respalda la legislación nacional que indica no repetir la prueba en un animal...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bovino; Tuberculosis; Intradermorreacción; Reacción tuberculínica.
Ano: 2007 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-34982007000100003
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Tuberculosis en Rhea Americana y Gallus Sp. en cautiverio InVet
Jorge,M.C; Traversa,M.J; Schettino,D.M; Bernardelli,A; Zumárraga,M; Cataldi,A; Romero,C; Grand,H.M.
La tuberculosis aviar tiene, distribución mundial y afecta a las aves domésticas y silvestres. El agente etiológico es Mycobacterium avium subsp. avium. El potencial zoonótico de esta enfermedad ha adquirido relevancia con la pandemia de HIV por ello todas las maniobras que involucren la manipulación de microorganismos viables, deben ser llevadas a cabo con adecuadas medidas de bioseguridad. La fuente primaria de infección es el ambiente contaminado con este agente. La presentación clínica es variable y el método definitivo para confirmar la infección es el aislamiento. El objetivo fue identificar mediante histopatología, bacteriología y biología molecular la etiología de lesiones compatibles con tuberculosis en una raza ornamental de Gallus sp. (sedosa...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aves; Rhea americana; Sedosa del Japón; Tuberculosis.
Ano: 2007 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-34982007000100004
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USE OF HONEY AS NUTRITIONAL AND THERAPEUTIC SUPPLEMENT IN THE TREATMENT OF INFECTIOUS DISEASES J. Venom. Anim. Toxins
PEREIRA,P.C.M.; BARRAVIERA,B.; BURINI,R.C.; SOARES,A.M.V.C.; BERTANI,M.A..
Honey, royal jelly, propolis, materials produced and/or gathered by Apis mellifera honeybees have been used as food and medication for centuries(6,7,8). Although extensively used, honeybee products have become a matter of interest and controversy for years. Honey, well known as healthy and natural food, has shown therapeutic properties in the treatment of digestive, respiratory, cardiac and rheumatic disorders, among others(4). Several studies have reported honey's immunological, antibacterial, antiinflammatory, antipyretic properties besides its importance in terms of energy intake(3,5). Furthermore, honey has proved to possesses wound healing and analgesic actions(1,2). Honey and propolis are also known to be effective in the treatment of respiratory...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Honey; Nutritional supplement; Apis mellifera; Paracoccidioidomycosis; Tuberculosis.
Ano: 1995 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301995000200006
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Lepromatous leprosy and perianal tuberculosis: a case report and literature review J. Venom. Anim. Toxins incl. Trop. Dis.
Parise-Fortes,Maria Rita; Lastória,Joel Carlos; Marques,Silvio Alencar; Putinatti,Maria Stella Ayres; Stolf,Hamilton Ometto; Marques,Mariângela Ester Alencar; Haddad,Vidal.
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a microorganism that usually affects skin and nerves. Although it is usually well-controlled by multidrug therapy (MDT), the disease may be aggravated by acute inflammatory reaction episodes that cause permanent tissue damage particularly to peripheral nerves. Tuberculosis is predominantly a disease of the lungs; however, it may spread to other organs and cause an extrapulmonary infection. Both mycobacterial infections are endemic in developing countries including Brazil, and cases of coinfection have been reported in the last decade. Nevertheless, simultaneous occurrence of perianal cutaneous tuberculosis and erythema nodosum leprosum is very rare, even in countries where both...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Mycobacteria; Leprosy; Tuberculosis; Erythema nodosum leprosum.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200506
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Trends in multidrug-resistant tuberculosis J. Venom. Anim. Toxins incl. Trop. Dis.
Dias-Baptista,I. M. F.; Usó,S. M. R. S.; Marcondes-Machado,J..
Multidrug-resistant tuberculosis (MDR-TB) is an increasing global problem. The extent and burden of MDR-TB varies significantly from country to country and region to region. Globally, about three per cent of all newly diagnosed patients have MDR-TB and the proportion is higher in patients who had previously received anti-tuberculosis (anti-TB) treatment reflecting the failure of programs designed to ensure complete cure of patients with tuberculosis. The management of MDR-TB is a challenge that should be undertaken by experienced clinicians at centers equipped with reliable laboratory services and implementation of DOTS-Plus strategy.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; MDR-TB; XDR-TB; DOTS; DOTS-Plus.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000200003
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A lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control J. Venom. Anim. Toxins incl. Trop. Dis.
Oliveira,Marcela de; Duarte,Sergio Barbosa; Giacomini,Guilherme; Pereira,Paulo Câmara Marques; Souza,Lenice do Rosário de; Miranda,José Ricardo de Arruda; Pina,Diana Rodrigues de.
Abstract Background: Background: Tuberculosis (TB) is an infectious lung disease with high worldwide incidence that severely compromises the quality of life in affected individuals. Clinical tests are currently employed to monitor pulmonary status and treatment progression. The present study aimed to apply a three-dimensional (3D) reconstruction method based on chest radiography to quantify lung-involvement volume of TB acute-phase patients before and after treatment. In addition, these results were compared with indices from conventional clinical exams to show the coincidence level. Methods: A 3D lung reconstruction method using patient chest radiography was applied to quantify lung-involvement volume using retrospective examinations of 50 patients who...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; Quantification; Lung involvement; Serum tests; Pulmonary function tests.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100302
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Review: genital tuberculosis in cattle and water buffaloes MV&Z
Castro Nassar, Alessandra Figueiredo de; Roxo, Eliana; Castro Portuga, Manuel Alberto da Silva.
Objective: To present a review on genital tuberculosis in caule and water buffaloes. Data Sources: the collections of the libraries of the Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo - FMVZlUSP (School of Veterinary Medicine and Animal Science of the University of São Paulo) and of the Instituto Biológico de São Paulo (São Paulo Biological lnstitute), as well as MEDLlNE database were searched, covering a retrospective period of 30 years. Data Synthesis: Tuberculosis is a public health concern and an economically important disease, responsible for big losses in caule husbandry. The zoonotic aspect of tuberculosis has decreased since the introduction of obligatory milk pasteurization, except in countries where the consumption...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; Genital; Mycobacterium bovis; Infertility; Caltle; Buffaloes Tuberculosis de los genitales; Mycobacterium bovis; Infertilidad; Bovillos; Búfalos tuberculose dos genitais; Mycobacterium bovis; Infertilidade; Bovinos; Búfalos.
Ano: 2005 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/3133
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Cellular profile of mares colostrum: a preliminary study MV&Z
Simon, Bruna Busianov Zaharov; Roncati, Neimar Vanderlei; Hoge, Alma Yasodhara Alexandra; Porto, Ana Carolina Rusca Correa.
There are few reports on which leukocytes are present in the colostrum and milk of mares. Recent studies in farm animals suggest a role for colostral leukocytes in the transfer of passive immunity from dam to neonate. The aim of this study was to characterize the population of leukocytes presentin colostrum from clinically healthy mares, using the light microscopy. Colostrum samples were collected from 20 mares,12 Mangalarga Marchador and 8 Quarter Horse. Macrophages were the predominant cell type in most samples studied followed by neutrophils and lymphocytes. These results may be a starting point for future studies investigating the role of colostral leukocytes in the transfer of immunity from mare to foal.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; Zoonoses; Human health; Mycobacterium bovis Colostro; Potros; Transferência de imunidade passiva; Leucócitos.
Ano: 2013 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/253
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Serological survey of Mycobacterium bovis, Brucella abortus and Borrelia burgdorferi in water buffaloes in the northern region of Brazil Rev Salud Anim.
Barbosa da Silva,Jenevaldo; da Fonseca,Adivaldo Henrique; Barbosa,José Diomedes.
The largest buffalo herds are in the northern region of Brazil, so few studies have been conducted to assess the prevalence of selected parasitic diseases in buffalo herds. The present study was therefore conducted to research the epidemiology of Borrelia burgdorferi, Mycobacterium bovis and Brucella abortus in water buffaloes in the north region of Brazil. A total of 4796 buffalo blood samples were randomly collected from five provinces and simultaneously analyzed by ELISA, tuberculin test, CFT and 2ME. The occurrence of B. burgdorferi in buffalo was 75% by ELISA. The tuberculin testing prevalence of M. bovis was 4.6%. The overall prevalence of B. abortus was 4.8% and 4.6% by CFT and 2ME, respectively. Thus, it is concluded that all agents studied were...
Tipo: Journal article Palavras-chave: Borreliosis; Brucellosis; Prevalence; Serology; Tuberculosis.
Ano: 2014 URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0253-570X2014000100006
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LAY USE OF AMAZONIAN PLANTS FOR THE TREATMENT OF TUBERCULOSIS Acta Amazonica
STOREY,Christine; SALEM,Júlia Ignez.
The Brazilian State of Amazonas has a high incidence of Tuberculosis, 91.4 in 10,000 habitants (SESAU, 1994) and resistant strains of Mycobacterium tuberculosis are frequently being found in the region (SALEM et.al, 1990). These problems have been associated with side effects caused by the antibiotics used to treat Tuberculosis, which have in rum been associated with treatment non-compliance (PATTISAPU, 1984). To resolve this problem a cost effective alternative treatment for Tuberculosis with few or no side effects, needs to be found. Amazonas has an abundance of plants, many of which are used by the lay population for medicinal purposes. A survey was carried out in five towns of the region, interviewing patients receiving treatment for Tuberculosis, to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; Amazonas; Medicinal plants; Lay beliefs.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59671997000300175
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PKO: alternative method for isolating mycobacteria from sputum Acta Amazonica
Salem,Julia Ignez; Carvalho,Clarice Maia; Ogusku,Mauricio Morishi; Maia,Rosália; Ruffino-Netto,Antonio.
We elaborated an alternative culture method, which we denominated PKO (initials in tribute of respect to Petroff, Kudoh and Ogawa), for isolating Mycobacterium tuberculosis from sputum for diagnosis of pulmonary tuberculosis (TB), and to compare its performance with the Swab and Petroff methods. For the technique validation, sputum samples from patients suspected of pulmonary TB cases were examined by acid-fast microscopy (direct and concentrated smear), PKO, Swab and Petroff methods. We found that Petroff and PKO methods have parity in the effectiveness of M. tuberculosis isolation. However, by the PKO method, 65% of isolated strains were detected in a period of <FONT FACE=Symbol>£</FONT>15 days, while by the Petroff method the best detection...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diagnostic method; Mycobacterium tuberculosis; PKO; Tuberculosis.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672007000300013
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Meta-análisis: diagnóstico de tuberculosis resistente por técnicas no comerciales de amplificación ABCL
Imperiale,Belén Rocío.
La emergencia de tuberculosis (TB) multidrogo y extensivamente-resistente reactivó la necesidad de contar con métodos rápidos para detectar resistencia a isoniacida (INH) y rifampicina (RIF). Por tal motivo, los objetivos de este trabajo fueron evaluar, mediante meta-análisis, la exactitud global y la posible utilidad de métodos caseros basados en PCR para la detección rápida de resistencia a INH y RIF en aislamientos clínicos de Mycobacterium tuberculosis. La búsqueda bibliográfica incluyó Medline/PubMed, BioMedLib. Para estimar la variabilidad entre los resultados de los estudios y el grado de exactitud diagnóstica de los métodos utilizados se realizaron gráficos "forest plot" y curvas SROC (summary receiver operating characteristic) mediante el software...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mycobacterium tuberculosis; Tuberculosis; Sensibilidad a drogas; Rifampicina; Isoniacida; Métodos moleculares; Reacción en cadena de la polimerasa; Métodos rápidos.
Ano: 2013 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-29572013000200017
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The re-emergency and persistence of vaccine preventable diseases Anais da ABC (AABC)
BORBA,RODRIGO C.N.; VIDAL,VINÍCIUS M.; MOREIRA,LILIAN O..
The introduction of vaccination worldwide dramatically reduced the incidence of pathogenic bacterial and viral diseases. Despite the highly successful vaccination strategies, the number of cases among vaccine preventable diseases has increased in the last decade and several of those diseases are still endemic in different countries. Here we discuss some epidemiological aspects and possible arguments that may explain why ancient diseases such as, measles, polio, pertussis, diphtheria and tuberculosis are still with us.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diphtheria; Measles; Pertussis; Polio; Tuberculosis; Vaccine.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000301311
Registros recuperados: 141
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