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| Kramer,C.K.; Leitão,C.B.; Azevedo,M.J.; Valiatti,F.B.; Rodrigues,T.C.; Canani,L.H.; Gross,J.L.. |
| Diabetic retinopathy has been associated with cardiac autonomic dysfunction in both type 1 and type 2 diabetes mellitus (DM) patients. Heart rate (HR) changes during exercise testing indicate early alterations in autonomous tonus. The aim of the present study was to investigate the association of diabetic retinopathy with exercise-related HR changes. A cross-sectional study was performed on 72 type 2 and 40 type 1 DM patients. Autonomic dysfunction was assessed by exercise-related HR changes (Bruce protocol). The maximum HR increase, defined as the difference between the peak exercise rate and the resting rate at baseline, and HR recovery, defined as the reduction in HR from the peak exercise to the HR at 1, 2, and 4 min after the cessation of the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Type 2 diabetes mellitus; Type 1 diabetes mellitus; Heart rate changes; Diabetic retinopathy. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001200011 |
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| Pozzan,R.; Dimetz,T.; Gazzola,H.M.; Gomes,M.B.. |
| In order to analyze the different parameters used in the interpretation of C-peptide response in a functional test, we compared a group of 26 type 1 diabetics aged 21.1 ± 8.2 years, with a diabetes duration of 7.9 ± 6.7 months, with a group of 24 non-diabetic subjects aged 25.0 ± 4.4 years. A standard mixed meal of 317 kcal was used as a stimulus. Blood sampling for C-peptide determinations was performed at regular intervals. Although all the studied C-peptide variables were significantly lower in the diabetic group (P<0.0001), some overlapping of parameters was observed between the two groups. The highest degree of overlapping was found for basal value (BV) (30.8%) and percent increase (42.31%), and the lowest for incremental area, absolute... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Type 1 diabetes mellitus; C-peptide response; Mixed meal test; Beta cell function. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000005 |
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| Rodacki,M.; Zajdenverg,L.; Albernaz,M.S.; Bencke-Gonçalves,M.R.; Milech,A.; Oliveira,J.E.P.. |
| The objective of the present study was to determine whether the duration of disease has any influence on the prevalence of glutamic acid decarboxylase autoantibodies (GADA) in Brazilian patients with type 1 diabetes (T1D) and variable disease duration. We evaluated 83 patients with T1D. All participants were interviewed and blood was obtained for GADA measurement by a commercial radioimmunoassay (RSR Limited, Cardiff, UK). Four groups of patients were established according to disease duration: A) 1-5 years of disease (N = 24), B) 6-10 years of disease (N = 19), C) 11-15 years of disease (N = 25), and D) >15 years of disease (N = 15). GADA prevalence and its titers were determined in each group. GADA was positive in 38 patients (45.8%) and its frequency... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anti-GAD65 auto-antibodies; Type 1 diabetes mellitus; Time from diagnosis. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001100008 |
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