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	Provedor de dados BJMBR (1) Autor Christoffolete,M.A. (1) Moriscot,A.S. (1) Palavra-chave Hypercaloric diet (1) Hypothyroidism (1) Thyroid hormone (1) UCP3 (1) Uncoupling protein (1) Tipo do documento Info:eu-repo/semantics/other (1) Ano 2004 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Hypercaloric cafeteria-like diet induced UCP3 gene expression in skeletal muscle is impaired by hypothyroidism BJMBR Christoffolete,M.A.; Moriscot,A.S.. The uncoupling protein UCP3 belongs to a family of mitochondrial carriers located in the inner mitochondrial membrane of certain cell types. It is expressed almost exclusively at high levels in skeletal muscle and its physiological role has not been fully determined in this tissue. In the present study we have addressed the possible interaction between a hypercaloric diet and thyroid hormone (T3), which are strong stimulators of UCP3 gene expression in skeletal muscle. Male Wistar rats weighing 180 ± 20 g were rendered hypothyroid by thyroidectomy and the addition of methimazole (0.05%; w/v) to drinking water after surgery. The rats were fed a hypercaloric cafeteria diet (68% carbohydrates, 13% protein and 18% lipids) for 10 days and sacrificed by... Tipo: Info:eu-repo/semantics/other Palavras-chave: Thyroid hormone; Hypothyroidism; Hypercaloric diet; Uncoupling protein; UCP3. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000600019 Registros recuperados: 1 Primeira ... 1 ... Última

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