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	Provedor de dados BJMBR (1) Autor Carvalho,A.F. (1) Fonteles,M.C. (1) Forte,L.R. (1) Santos-Neto,M.S. (1) Palavra-chave ANP (1) CGMP (1) Guanylin (1) Kidney (1) Natriuresis (1) Uroguanylin (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 1999 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Relationship between the actions of atrial natriuretic peptide (ANP), guanylin and uroguanylin on the isolated kidney BJMBR Santos-Neto,M.S.; Carvalho,A.F.; Forte,L.R.; Fonteles,M.C.. Guanylin and uroguanylin are peptides that bind to and activate guanylate cyclase C and control salt and water transport in many epithelia in vertebrates, mimicking the action of several heat-stable bacteria enterotoxins. In the kidney, both of them have well-documented natriuretic and kaliuretic effects. Since atrial natriuretic peptide (ANP) also has a natriuretic effect mediated by cGMP, experiments were designed in the isolated perfused rat kidney to identify possible synergisms between ANP, guanylin and uroguanylin. Inulin was added to the perfusate and glomerular filtration rate (GFR) was determined at 10-min intervals. Sodium was also determined. Electrolyte dynamics were measured by the clearance formula. Guanylin (0.5 µg/ml, N = 12) or uroguanylin... Tipo: Info:eu-repo/semantics/article Palavras-chave: ANP; Guanylin; Uroguanylin; Kidney; Natriuresis; CGMP. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000800012 Registros recuperados: 1 Primeira ... 1 ... Última

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