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Action of calcium binders.: Formation of calcium salts in the intestinal tract and the blood circulatory system ABCL
Martínez Yaquelo,César.
Calcium binders are water- soluble substances whose anionic part can possibly react with calcium cations present in any part of the human body. Some examples of calcium binders are phosphoric, oxalic and phytic acids and their alkaline salts present in many natural foods, in some foods containing additives, and in some medicines. There are also uric and lactic acids that are the result of normal metabolism. The first negative action of calcium binders takes place in the intestinal tract when they react with calcium of dairy food. The latter produces a combination of calcium binder anions with calcium cations, and then an insoluble salt that precipitates as small solid particles that cannot be assimilated and which are eliminated in the faeces. The second...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Calcium binders; Osteopenia; Osteoporosis; Atherosclerosis; Nephrosclerosis; Urolithyasis; Calcinosis; Vascular calcification.
Ano: 2006 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-29572006000200008
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Bone metabolism and vascular calcification BJMBR
Danilevicius,C.F.; Lopes,J.B.; Pereira,R.M.R..
Osteoporosis and atherosclerosis are chronic degenerative diseases which have been considered to be independent and whose common characteristic is increasing incidence with age. At present, growing evidence indicates the existence of a correlation between cardiovascular disease and osteoporosis, irrespective of age. The morbidity and mortality of osteoporosis is mainly related to the occurrence of fractures. Atherosclerosis shows a high rate of morbidity and especially mortality because of its clinical repercussions such as angina pectoris, acute myocardial infarction, stroke, and peripheral vascular insufficiency. Atherosclerotic disease is characterized by the accumulation of lipid material in the arterial wall resulting from autoimmune and inflammatory...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Osteoporosis; Vascular calcification; Atherosclerosis; Low-bone mineral density; Arterial calcification.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000400001
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Lipoic acid, but not tempol, preserves vascular compliance and decreases medial calcification in a model of elastocalcinosis BJMBR
Bassi,E.; Liberman,M.; Martinatti,M.K.; Bortolotto,L.A.; Laurindo,F.R.M..
Vascular calcification decreases compliance and increases morbidity. Mechanisms of this process are unclear. The role of oxidative stress and effects of antioxidants have been poorly explored. We investigated effects of the antioxidants lipoic acid (LA) and tempol in a model of atherosclerosis associated with elastocalcinosis. Male New Zealand white rabbits (2.5-3.0 kg) were fed regular chow (controls) or a 0.5% cholesterol (chol) diet+104 IU/day vitamin D2 (vitD) for 12 weeks, and assigned to treatment with water (vehicle, n=20), 0.12 mmol·kg-1·day-1 LA (n=11) or 0.1 mmol·kg-1·day-1 tempol (n=15). Chol+vitD-fed rabbits developed atherosclerotic plaques associated with expansive remodeling, elastic fiber disruption, medial calcification, and increased...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidants; Vascular calcification; Atherosclerosis; Oxidative stress; Lipoic acid.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000200119
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