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	Provedor de dados BJMBR (4) Autor Brum,P.C. (2) Vanzelli,A.S. (2) Aguilera,N.W. (1) Bacurau,A.V.N. (1) Bonatto,R.C. (1) Bregagnollo,E.A. (1) Cicogna,A.C. (1) Ferreira,J.C.B. (1) Fioretto,J.R. (1) Irigoyen,M.C. (1) Martins,A.S. (1) Matsubara,B.B. (1) Medeiro,A. (1) Medeiros,A. (1) Negrão,C.E. (1) Okoshi,K. (1) Okoshi,M.P. (1) Padovani,C.R. (1) Rosa,K.T. (1) Tucci,P.J.F. (1) Mais... Palavra-chave Ventricular function (4) Cardiac remodeling (2) Exercise training (2) Heart failure (2) Afterload (1) Carvedilol treatment (1) DP/dt (1) DT/dt (1) Experimental model (1) Isometric contractions (1) Papillary muscle (1) Skeletal myopathy (1) Sympathetic hyperactivity (1) Ventricular hypertrophy (1) Α2A/α2CArKO mice (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Info:eu-repo/semantics/other (1) Ano 2011 (1) 2008 (1) 2001 (1) 1997 (1) País Brazil (4) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Aerobic exercise training in heart failure: impact on sympathetic hyperactivity and cardiac and skeletal muscle function BJMBR Brum,P.C.; Bacurau,A.V.N.; Medeiros,A.; Ferreira,J.C.B.; Vanzelli,A.S.; Negrão,C.E.. Heart failure is a common endpoint for many forms of cardiovascular disease and a significant cause of morbidity and mortality. Chronic neurohumoral excitation (i.e., sympathetic hyperactivity) has been considered to be a hallmark of heart failure and is associated with a poor prognosis, cardiac dysfunction and remodeling, and skeletal myopathy. Aerobic exercise training is efficient in counteracting sympathetic hyperactivity and its toxic effects on cardiac and skeletal muscles. In this review, we describe the effects of aerobic exercise training on sympathetic hyperactivity, skeletal myopathy, as well as cardiac function and remodeling in human and animal heart failure. We also discuss the mechanisms underlying the effects of aerobic exercise training. Tipo: Info:eu-repo/semantics/article Palavras-chave: Heart failure; Exercise training; Sympathetic hyperactivity; Ventricular function; Cardiac remodeling; Skeletal myopathy. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000900002 The rate of force generation by the myocardium is not influenced by afterload BJMBR Fioretto,J.R.; Okoshi,M.P.; Okoshi,K.; Cicogna,A.C.; Bonatto,R.C.; Padovani,C.R.; Tucci,P.J.F.. The influence of afterload on the rate of force generation by the myocardium was investigated using two types of preparations: the in situ dog heart (dP/dt) and isolated papillary muscle of rats (dT/dt). Thirteen anesthetized, mechanically ventilated and thoracotomized dogs were submitted to pharmacological autonomic blockade (3.0 mg/kg oxprenolol plus 0.5 mg/kg atropine). A reservoir connected to the left atrium permitted the control of left ventricular end-diastolic pressure (LVEDP). A mechanical constriction of the descending thoracic aorta allowed to increase the systolic pressure in two steps of 20 mmHg (conditions H1 and H2) above control values (condition C). After arterial pressure elevations (systolic pressure C: 119 ± 8.1; H1: 142 ± 7.9; H2 166 ±... Tipo: Info:eu-repo/semantics/article Palavras-chave: Ventricular function; Afterload; DP/dt; DT/dt; Papillary muscle; Isometric contractions. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001200015 Experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctation BJMBR Martins,A.S.; Aguilera,N.W.; Matsubara,B.B.; Bregagnollo,E.A.. Ascending aorta coarctation was produced by a minimally invasive technique in rabbits. Animal mortality was 5%. Morphometric and hemodynamic parameters were evaluated. A parabiotically isolated heart model was used to assess the hemodynamic parameters. Left ventricular weight/body weight ratio and muscle area showed clear evidence of hypertrophy when compared to control. The hemodynamic changes in the isolated heart model suggested decreased diastolic and systolic function in the coarcted group. The present model produced hypertrophy with low mortality rates as a result of its less invasive nature. Tipo: Info:eu-repo/semantics/other Palavras-chave: Ventricular hypertrophy; Ventricular function; Experimental model. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300017 Effect of exercise training and carvedilol treatment on cardiac function and structure in mice with sympathetic hyperactivity-induced heart failure BJMBR Medeiro,A.; Vanzelli,A.S.; Rosa,K.T.; Irigoyen,M.C.; Brum,P.C.. The present investigation was undertaken to study the effect of β-blockers and exercise training on cardiac structure and function, respectively, as well as overall functional capacity in a genetic model of sympathetic hyperactivity-induced heart failure in mice (α2A/α2CArKO). α2A/α2CArKO and their wild-type controls were studied for 2 months, from 3 to 5 months of age. Mice were randomly assigned to control (N = 45), carvedilol-treated (N = 29) or exercise-trained (N = 33) groups. Eight weeks of carvedilol treatment (38 mg/kg per day by gavage) or exercise training (swimming sessions of 60 min, 5 days/week) were performed. Exercise capacity was estimated using a graded treadmill protocol and HR was measured by tail cuff. Fractional shortening was... Tipo: Info:eu-repo/semantics/article Palavras-chave: Heart failure; Exercise training; Carvedilol treatment; Ventricular function; Cardiac remodeling; Α2A/α2CArKO mice. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000900012 Registros recuperados: 4 Primeira ... 1 ... Última

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