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	Provedor de dados BJMBR (2) Autor San Martin,S. (1) Sobel,R.A. (1) Soto-Suazo,M. (1) Zorn,T.M.T. (1) Palavra-chave Proteoglycans (2) Versican (2) Axon regeneration (1) Central nervous system (1) Decidualization (1) Endometrium (1) Extracellular matrix (1) Hyaluronan (1) Mouse (1) Multiple sclerosis (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2003 (1) 2001 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Distribution of versican and hyaluronan in the mouse uterus during decidualization BJMBR San Martin,S.; Soto-Suazo,M.; Zorn,T.M.T.. Preparation for embryo implantation requires extensive adaptation of the uterine microenvironment. This process consists of cell proliferation and cell differentiation resulting in the transformation of endometrial fibroblasts into a new type of cell called decidual cell. In the present study, we followed the space-time distribution of versican and hyaluronan (HA) in different tissues of the uterus before and after embryo implantation. Fragments of mouse uteri obtained on the fourth, fifth, sixth and seventh days of pregnancy were fixed in Methacarn, embedded in Paraplast and cut into 5-µm thick sections. HA was detected using a biotinylated fragment of the proteoglycan aggrecan, which binds to this glycosaminoglycan with high affinity and specificity.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Decidualization; Endometrium; Proteoglycans; Versican; Hyaluronan; Mouse. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000800013 The extracellular matrix in multiple sclerosis: an update BJMBR Sobel,R.A.. Extracellular matrix (ECM) molecules play important roles in the pathobiology of the major human central nervous system (CNS) inflammatory/demyelinating disease multiple sclerosis (MS). This mini-review highlights some recent work on CNS endothelial cell interactions with vascular basement membrane ECM as part of the cellular immune response, and roles for white matter ECM molecules in demyelination and remyelination in MS lesions. Recent basic and clinical investigations of MS emphasize axonal injury, not only in chronic MS plaques, but also in acute lesions; progressive axonal degeneration in normal-appearing white matter also may contribute to brain and spinal cord atrophy in MS patients. Remodeling of the interstitial white matter ECM molecules that... Tipo: Info:eu-repo/semantics/article Palavras-chave: Axon regeneration; Central nervous system; Extracellular matrix; Proteoglycans; Multiple sclerosis; Versican. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000500007 Registros recuperados: 2 Primeira ... 1 ... Última

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