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	Provedor de dados BJID (1) PAB (1) Autor Badaró,Roberto (1) Bahia,Fabianna (1) Brites,Carlos (1) Dusi,André Nepomuceno (1) Gilbert,Mark (1) Melo,Paulo Eduardo de (1) Oliveira,Cristiane Lopes de (1) Pedroso,Célia (1) Torres,Antonio Carlos (1) Mais... Palavra-chave Viral resistance (2) Brazil (1) Coat protein gene (1) Genetically modified organism (1) HIV-1 (1) Solanum tuberosum (1) Transgenic potato (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2009 (1) 2001 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Evaluation of viral resistance to Reverse Transcriptase Inhibitors (RTI) in HIV-1-infected patients before and after 6 months of single or double antiretroviral therapy BJID Brites,Carlos; Bahia,Fabianna; Gilbert,Mark; Pedroso,Célia; Badaró,Roberto. We evaluated samples of peripheral blood mononuclear (PBMC) cells from 46 AIDS patients, before starting therapy with HIV-1 reverse transcriptase inhibitors (RTI), and after 6 months of drug use. PBMC were stored and tested by a Line Probe Assay (LiPA), in order to assess the frequency of RT mutations in this population. Six patients were taking AZT before initial blood collection (1 to 16 weeks of drug use) and 40 patients had no prior therapy. After baseline evaluation, 19 patients received AZT, 23 AZT plus DDI, 3 started AZT only with DDI added after 3 months, and 3 received a combination of AZT plus 3TC. Detection of at least one mutation was found in 33% (15/46) of patients at baseline, and 83% (38/46) had at least 1 mutation after 6 months of... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV-1; Viral resistance; Brazil. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000400003 Resistance of genetically modified potatoes to Potato virus Y under field conditions PAB Dusi,André Nepomuceno; Oliveira,Cristiane Lopes de; Melo,Paulo Eduardo de; Torres,Antonio Carlos. The objective of this work was to evaluate the resistance of genetically modified clones of potato to Potato virus Y (PVY) under field conditions. Genetically modified plants were compared with nontransformed plants of the same cultivar. The plots were flanked with potato plants infected with both PVYº and PVY N strains (spread lines), in order to provide the experimental area with the source of virus, which was naturally spread by the native aphid population. The experiment was weekly monitored by visual inspections and by DAS-Elisa in the plants produced from the harvested tubers, in order to evaluate the resistance of transgenic plants throughout the plant growth cycle. By the end of the third year, no infection symptoms were observed in the 1P clone;... Tipo: Info:eu-repo/semantics/article Palavras-chave: Solanum tuberosum; Coat protein gene; Genetically modified organism; Transgenic potato; Viral resistance. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2009000900009 Registros recuperados: 2 Primeira ... 1 ... Última

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