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| Lucinda,Leda M.F.; Rocha,Camila B.; Reboredo,Maycon M.; Faria,Vinícius C.; Sá,Rita C.S.. |
| Caesalpinia ferrea Mart (Leguminosae) is a medicinal plant used to treat diabetes, among other therapeutic properties, but which is also reported to have hepatotoxic effects. Although it contains substances such as flavonoids and coumarin, which are known to have antifertility activity, no studies have apparently been conducted to evaluate the potential adverse side effects of this plant on the function of the reproductive system after a chronic treatment. Therefore, this investigation was carried out to evaluate the effect and safety of the long-term exposure to C. ferrea on male Wistar rats' vital organs, reproductive system and sperm production. Adult and immature male rats were treated with an aqueous extract of C. ferrea at a dose level of 300 mg/kg... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Caesalpinia ferrea; Wistar rat; Reproductive system; Toxicological assessment; Chronic and sub-chronic treatment. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652010000400013 |
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| Sá,Rita de Cássia da Silveira e; Leite,Magda Narciso; Peters,Vera Maria; Guerra,Martha de Oliveira; Almeida,Reinaldo Nóbrega de. |
| This work makes an assessment of the dominant lethality of Mikania glomerata in male Wistar rats. Adult male received 1 mL of M. glomerata hydroalcoholic extract at a dose level of 3.3 g/kg body weight for 52 days and were mated with untreated females for seven weeks (group 1) or one week prior to the beginning of treatment and on the week following the end of treatment (group 2). The parameters analyzed were: number of implanted embryos, resorptions and corpora lutea; mating, gestation, preimplantation loss, implantation and resorption indexes (group 1); number of offspring and weaning animals (group 2). The administration of M. glomerata did not show any impairment of fertility and no significant difference in the parameters analyzed, suggesting an... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mikania glomerata; Mutagenicity; Wistar rat. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500009 |
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| Silva,Hilton Justino da; Barros,Karla Mônica Ferraz Teixeira de; Cunha,Daniele Andrade da; Santos,Francisco de Assis da Silva; Soares,Elisângela Barros; Silva,Clécia Natália de Siqueira da; Moraes,Silvia Regina Arruda de; Castro,Raul Manhães de. |
| This study analyzed the consequence of malnutrition and/or serotoninergic manipulation during the period of fast growth of encephalon on the somatic development in rats. It was used the protocol of measurement of indicators of this development proposed by Silva et al., 2005. The protocol was applied from 1st to 21st day and rats were breastfed by female which received control diet (commercial diet, Labina) with 23% of protein, normoproteic diet, nourished animals (Group Nourished Nour), n=15 or were breastfed by female which after the delivery received hypoproteic diet (Regional Basic Diet RBD), with 8% of protein, malnourished animals (Group Malnourished Maln) n=15. It were observed in the group malnourished a decrease of corporal weight from 4th... |
| Tipo: Journal article |
Palavras-chave: Malnutrition; Somatic development; Wistar rat. |
| Ano: 2006 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000400028 |
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| Saalu,L. C; Akunna,G. G; Oyewopo,A. O. |
| Vernonia amygdalina (bitter-leaf) is native to West Africa but occurs mostly in its cultivated form in various parts of central and southern Nigeria. It is a dark-green leafy vegetable commonly used in cooking and as folkloric medicine for the management of several diseases in Nigeria. In the present study, the effects of varying doses of ethanolic leaf extract of Vernonia amygdalina on the rat testis histo-morphometry were investigated. Forty male wistar rats were divided into groups of four. Group A, as the control was given 10 ml/kg/day/oral distilled water while Group B, C and D subsequently treated with 100, 300 and 600 mg/kg/day/oral route Vernonia amygdalina leaves extract respectively for 56 days. Results showed that Group B rats had normal testis... |
| Tipo: Journal article |
Palavras-chave: Vernonia amygdalina; Histology; Morphometry; Testis; Wistar rat. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200052 |
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