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	Provedor de dados BJMBR (2) Autor Tedesco,A.C. (2) Lunardi,C.N. (1) Nunes,S.M.T. (1) Rotta,J.C.G. (1) Sguilla,F.S. (1) Palavra-chave Liposomes (2) Zinc phthalocyanine (2) Bovine serum albumin (1) Cardiolipin (1) Chloroaluminum phthalocyanine (1) Cholesterol (1) Dimyristoyl phosphatidylcholine (1) Nitric oxide (1) Photodynamic therapy (1) S-nitrosothiols (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2004 (1) 2003 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Nitric oxide release from the S-nitrosothiol zinc phthalocyanine complex by flash photolysis BJMBR Rotta,J.C.G.; Lunardi,C.N.; Tedesco,A.C.. The photogeneration of nitric oxide (NO) using laser flash photolysis was investigated for S-nitroso-glutathione (GSNO) and S-nitroso-N-acetylcysteine (NacySNO) at pH 6.4 (PBS/HCl) and 7.4 (PBS). Irradiation of S-nitrosothiol with light (lambda = 355 nm followed by absorption spectroscopy) resulted in the homolytic decomposition of NacySNO and GSNO to generate radicals (GS· and NacyS·) and NO. The release of NO from donor compounds measured with an ISO-Nometer apparatus was larger at pH 7.4 than pH 6.4. NacySNO was also incorporated into dipalmitoyl-phosphatidylcholine liposomes in the presence and absence of zinc phthalocyanine (ZnPC), a well-known photosensitizer useful for photodynamic therapy. Liposomes are usually used as carriers for hydrophobic... Tipo: Info:eu-repo/semantics/article Palavras-chave: S-nitrosothiols; Nitric oxide; Zinc phthalocyanine; Liposomes; Photodynamic therapy. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000500005 Photophysical studies of zinc phthalocyanine and chloroaluminum phthalocyanine incorporated into liposomes in the presence of additives BJMBR Nunes,S.M.T.; Sguilla,F.S.; Tedesco,A.C.. The photophysical properties of zinc phthalocyanine (ZnPC) and chloroaluminum phthalocyanine (AlPHCl) incorporated into liposomes of dimyristoyl phosphatidylcholine in the presence and absence of additives such as cholesterol or cardiolipin were studied by time-resolved fluorescence, laser flash photolysis and steady-state techniques. The absorbance of the drugs changed linearly with drug concentration, at least up to 5.0 µM in homogeneous and heterogeneous media, indicating that aggregation did not occur in these media within this concentration range. The incorporation of the drugs into liposomes increases the dimerization constant by one order of magnitude (for ZnPC, 3.6 x 10(4) to 1.0 x 10(5) M-1 and for AlPHCl, 3.7 x 10(4) to 1.5 x 10(5) M-1), but this... Tipo: Info:eu-repo/semantics/article Palavras-chave: Zinc phthalocyanine; Chloroaluminum phthalocyanine; Bovine serum albumin; Liposomes; Cholesterol; Cardiolipin; Dimyristoyl phosphatidylcholine. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000200016 Registros recuperados: 2 Primeira ... 1 ... Última

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