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Histological and Histochemical Studies of the Aorta and Pulmonary Trunk in STZ-induced Diabetic Wistar Rats Treated with Momordica charantia International Journal of Morphology
Komolafe,O. A; Ofusori,D. A; Adewole,O. S; Ayoka,A. O; Bejide,R.
Diabetes mellitus (DM) is a serious metabolic disorder with micro and macro-vascular complications that result in a significant morbidity and mortality. The present study investigated the effects of Momordica charantia (M. charantia) on histological changes of the aorta and pulmonary trunk in streptozotocin-induced diabetic Wistar rats. Forty healthy adult Wistar rats of both sexes were randomly assigned into five groups A, B, C, D and E of eight rats each. Group A were the control (normal rats); B were the experimentally-induced diabetic rats; C were diabetic rats treated with methanolic extracts of M. charantia for two weeks (withdrawal group); D were diabetic rats treated with methanolic extracts of M. charantia for four weeks. E was diabetic rats...
Tipo: Journal article Palavras-chave: Diabetes; Momordica charantia; Histological; Histochemistry; Aorta; Pulmonary trunk.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200060
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Ultrastructural and Immunohistochemical Effects of Aqueous Leave Extract of Xylopia aethiopica on the Stomach in Streptozotocin-Induced Diabetic Rats International Journal of Morphology
Ofusori,D. A; Komolafe,O. A; Adewole,O. S; Arayombo,B. E; Margolis,D; Naicker,T.
Gastrointestinal pathology in diabetic patients has become a source of concern in recent times. The aim of this study was to investigate the ultrastructural and immunohistochemical effects of aqueous leaf extract of Xylopia aethiopica on the stomach in streptozotocin-induced diabetic rats. This study was conducted using thirty adult Wistar rats. The animals were divided into three groups (n= 10). Group A was the control animals (administered with equivalent volume of citrate buffer), group B was diabetic animals induced by a single intraperitoneal injection of streptozotocin dissolved in citrate buffer (65 mg/kg) and group C was diabetic animals treated with 200 mg/kg body weight of aqueous leave extract of X. aethiopica for twenty five days. At the...
Tipo: Journal article Palavras-chave: Diabetes mellitus; Immunohistochemistry; Ultrastructure; Stomach; Xylopia aethiopic.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100006
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