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| Destaillats, F.; Joffre, C.; Acar, N.; Joffre, F.; Bezelgues, J.B.; Pasquis, B.; Cruz-Hernandez, C.; Rezzi, S.; Montoliu, I.; Dionisi, F.; Bretillon, L.. |
| Background: Dietary long-chain polyunsaturated fatty acids (LC-PUFA) are of crucial importance for the development of neural tissues. The aim of this study was to evaluate the impact of a dietary supplementation in n-3 fatty acids in female rats during gestation and lactation on fatty acid pattern in brain glial cells phosphatidylethanolamine (PE) and phosphatidylserine (PS) in the neonates.Methods: Sprague-Dawley rats were fed during the whole gestation and lactation period with a diet containing either docosahexaenoic acid (DHA, 0.55%) and eicosapentaenoic acid (EPA, 0.75% of total fatty acids) or α-linolenic acid (ALA, 2.90%). At two weeks of age, gastric content and brain glial cell PE and PS of rat neonates were analyzed for their fatty acid and... |
| Tipo: Journal Article |
Palavras-chave: POLYUNSATURED FATTY ACID; GESTATION; LACTATION; NEURAL TISSUES; DIETARY SUPPLEMENTATION. |
| Ano: 2010 |
URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD20108732ec2d&uri=/notices/prodinra1/2010/07/ |
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