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Registros recuperados: 40
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A single nucleotide polymorphism in NEUROD1 is associated with production traits in nelore beef cattle. Repositório Alice
OLIVEIRA, P. P. A.; TIZIOTO, P. C.; MALAGO JUNIOR, W.; NASCIMENTO, M. L. do; CESAR, A. S. M.; DINIZ, W. J. da S.; SOUZA, M. M. de; LANNA, D. P. D.; TULLIO, R. R.; MOURAO, G. B.; MUDADU, M. de A.; COUTINHO, L. L.; REGITANO, L. C. de A..
Feed efficiency and carcass characteristics are late-measured traits. The detection of molecular markers associated with them can help breeding programs to select animals early in life, and to predict breeding values with high accuracy. The objective of this study was to identify polymorphisms in the functional and positional candidate gene NEUROD1 (neurogenic differentiation 1), and investigate their associations with production traits in reference families of Nelore cattle. A total of 585 steers were used, from 34 sires chosen to represent the variability of this breed. By sequencing 14 animals with extreme residual feed intake (RFI) values, seven single nucleotide polymorphisms (SNPs) in NEUROD1 were identified. The investigation of marker effects on...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Candidate gene; Feed efficiency; Bos Indicus; Body composition.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1053741
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Allele specific expression analysis in bovine muscle tissue. Repositório Alice
SOUZA, M. M.; MOKRY, F. C.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A.; CESAR, A. S. M.; MORÉ, D.; MOURÃO, G.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; ZERLOTINI, A.; REGITANO, L. C..
2015
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Allele; Specific expression analysis; Bovine muscle tissue.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1029313
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Allele specific expression analysis in bovine muscle tissue. Repositório Alice
SOUZA, M. M.; MOKRY, F. C.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A.; CESAR, A. S. M.; MORÉ, D.; MOURÃO, G.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; COUTINHO, L. L.; ZERLOTINI NETO, A.; REGITANO, L. C..
Imprinted genes have been target of many studies, mainly in human and mouse, and lately in bovines due to the interest of understanding the epigenetic mechanisms underlying important meat quality phenotypes and the possibility of applying it in animal breeding programs in the future. Genomic DNA from 146 steers was genotyped using the Illumina BovineHD BeadChip in order to identify heterozygous individuals with known allele origin.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bioinformática; Expressão gênica; Genoma; Bioinformatics; Gene expression; Genome.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1035220
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Allele specific expression analysis in bovine muscle tissue. Repositório Alice
SOUZA, M. M.; MOKRY, F. C.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A.; CESAR, A. S. M.; MORÉ, D.; MOURÃO, G.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; COUTINHO, L. L.; ZERLOTINI, A.; REGITANO, L. C..
Imprinted genes have been target of many studies, mainly in human and mouse, and lately in bovines due to the interest of understanding the epigenetic mechanisms underlying important meat quality phenotypes and the possibility of applying it in animal breeding programs in the future. Genomic DNA from 146 steers was genotyped using the Illumina BovineHD BeadChip in order to identify heterozygous individuals with known allele origin.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bioinformática; Expressão gênica; Genoma; Bioinformatics; Genome; Gene expression.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1035029
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An integrative transcriptome analysis indicates regulatory mRNA-miRNA networks for residual feed intake in Nelore cattle. Repositório Alice
OLIVEIRA, P. S. N. de; COUTINHO, L. L.; TIZIOTO, P. C.; CESAR, A. S. M.; OLIVEIRA, G. B. de; DINIZ, W, J. da S.; LIMA, A. O. de; REECY, J. M.; MOURÃO, G. B.; ZERLOTINI NETO, A.; REGITANO, L. C. de A..
Residual Feed Intake (RFI) is an economically relevant trait in beef cattle. Among the molecular regulatory mechanisms, microRNAs (miRNAs) are an important dimension in post-transcriptional regulation and have been associated with different biological pathways. Here, we performed differential miRNAs expression and weighted gene co-expression network analyses (WGCNA) to better understand the complex interactions between miRNAs and mRNAs expressed in bovine skeletal muscle and liver. MiRNA and mRNA expression data were obtained from Nelore steers that were genetically divergent for RFI (N = 10 [low RFI or feed efficient]; N = 10 [high RFI or feed inefficient]). Differentially expressed and hub miRNAs such as bta-miR-486, bta-miR-7, bta-miR15a, bta-miR-21,...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: MicroRNAs; Residual Feed Intake; Gado Nelore; Beef cattle; Nellore; Skeletal muscle.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1102149
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An integrative transcriptome analysis indicates regulatory mRNA-miRNA networks for residual feed intake in Nelore cattle. Repositório Alice
OLIVEIRA, P. S. N. de; COUTINHO, L. L.; TIZIOTO, P. C.; CESAR, A. S. M.; OLIVEIRA, G. B. de; DINIZ, W, J. da S.; LIMA, A. O. de; REECY, J. M.; MOURÃO, G. B.; ZERLOTINI NETO, A.; REGITANO, L. C. de A..
Residual Feed Intake (RFI) is an economically relevant trait in beef cattle. Among the molecular regulatory mechanisms, microRNAs (miRNAs) are an important dimension in post-transcriptional regulation and have been associated with different biological pathways. Here, we performed differential miRNAs expression and weighted gene co-expression network analyses (WGCNA) to better understand the complex interactions between miRNAs and mRNAs expressed in bovine skeletal muscle and liver. MiRNA and mRNA expression data were obtained from Nelore steers that were genetically divergent for RFI (N = 10 [low RFI or feed efficient]; N = 10 [high RFI or feed inefficient]). Differentially expressed and hub miRNAs such as bta-miR-486, bta-miR-7, bta-miR15a, bta-miR-21,...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: RFI; MiRNA; Gado Nelore; Beef cattle; Nellore; Skeletal muscle.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1099755
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Association of skeletal muscle transcripts with fatty acid content in Nellore cattle. Repositório Alice
CESAR, A. S. M.; REGITANO, L. C. de A.; POLETI, M. D.; ANDRADE, S. C. da S.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; LANNA, D. P. D.; TULLIO, R. R.; NASSU, R. T.; KOLTES, J. E.; WATERS, E. F.; REECY, J. M.; COUTINHO, L. L..
2016
Tipo: Artigo em anais de congresso (ALICE) Palavras-chave: Conjugated linoleic acid; Oleic acid; Differentially expressed genes.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1060623
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Co-expression network analysis identifies genes associated with iron content in bovine muscle. Repositório Alice
DINIZ, W. J. da S.; CESAR, A. S. M.; GEISTLINGER, L.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; AFONSO, J.; ROCHA, M. I. P.; LIMA, A. O. de; BUSS, C. E.; COUTINHO, L. L.; REGITANO, L. C. de A..
Editores: Luiz Lehmann Coutinho, ESALQ/USP; Luciana Correia de Almeida Regitano, Embrapa Pecuária Sudeste; Gerson Barreto Mourão, ESALQ/USP; Aline Silva Mello Cesar, ESALQ/USP; Bárbara Silva Vignato, FZEA/USP; Mirele Daiana Poleti, ESALQ/USP; Wellison Jarles da Silva Diniz, UFSCar.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Gene expression; Network analysis; Systems biology.
Ano: 2017 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1075630
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Co-expression network analysis identifies genes associated with meat tenderness. Repositório Alice
DINIZ, W. J. da S.; CESAR, A. S. M.; GEISTLINGER, L.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; AFONSO, J.; ROCHA, M. I. P.; LIMA, A. O. de; BUSS, C. E.; COUTINHO, L. L.; REGITANO, L. C. de A..
Tenderness is an important trait of meat quality and is known to be influenced by several factors including genetic composition.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Gene expression; Network analysis; System biology.
Ano: 2017 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1080848
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Comparative muscle transcriptome associated with carcass traits of Nellore cattle. Repositório Alice
VIGNATO, B. S.; COUTINHO, L. L.; CESAR, A. S. M.; POLETI, M. D.; REGITANO, L. C. de A.; BALIEIRO, J. C. de C..
Commercial cuts yield is an important trait for beef production, which affects the final value of the products, but its direct determination is a challenging procedure to be implemented in practice. The measurement of ribeye area (REA) and backfat thickness (BFT) can be used as indirect measures of meat yield. REA and BFT are important traits studied in beef cattle due to their strong implication in technological (carcass yield) and nutritional characteristics of meat products, like the degree of muscularity and total body fat. Thus, the aim of this work was to study the Longissimus dorsi muscle transcriptome of Nellore cattle, associated with REA and BFT, to find differentially expressed (DE) genes, metabolic pathways, and biological processes that may...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Backfat thickness; Bos taurus indicus; Ribeye area.
Ano: 2017 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1074816
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Complex pattern of CAST allelic expression in bovine muscle tissue. Repositório Alice
SOUZA, M. M.; ZERLOTINI, A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A. L.; MOKRY, F. B.; CESAR, A. S. M.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; COUTINHO, L. L.; REGITANO, L. C. A..
2014
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bioinformática; Polimorfismo de nucleotídeo único; Bioinformatics; Single nucleotide polymorphism.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1007540
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Copy number variations and genome-wide associations reveal putative genes and metabolic pathways involved with the feed conversion ratio in beef cattle. Repositório Alice
SANTANA, M. H. de A.; OLIVEIRA JUNIOR, G. A.; CESAR, A. S. M.; FREUA, M. C.; GOMES, R. da C.; SILVA, S. da L.; LEME, P. R.; FUKUMASU, H.; CARVALHO, M. E.; VENTURA, R. V.; COUTINHO, L. L.; KADARMIDEEN, H. N.; FERRAZ, J. B. S..
The use of genome-wide association results combined with other genomic approaches may uncover genes and metabolic pathways related to complex traits. In this study, the phenotypic and genotypic data of 1475 Nellore (Bos indicus) cattle and 941,033 single nucleotide polymorphisms (SNPs) were used for genome-wide association study (GWAS) and copy number variations (CNVs) analysis in order to identify candidate genes and putative pathways involved with the feed conversion ratio (FCR). The GWAS was based on the Bayes B approach analyzing genomic windows with multiple regression models to estimate the proportion of genetic variance explained by each window. The CNVs were detected with PennCNV software using the log R ratio and B allele frequency data. CNV...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Nellore cattle; GWAS; Cattle; Feed conversion; Genomics; Cucumber necrosis virus; Single nucleotide polymorphism.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1066092
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Detection of Co-expressed pathway modules associated with mineral concentration and meat quality in nelore cattle. Repositório Alice
DINIZ, W. J. S.; MAZZONI, G.; COUTINHO; BANERJEE, P.; GEISTLINGER, L.; CESAR, A. S. M.; BERTOLINI. F.; AFONSO, J.; OLIVEIRA, P. S. N.; TIZIOTO, P. C.; KADARMIDEEN, H. N.; REGITANO, L. C. de A..
Meat quality is a complex trait that is influenced by genetic and environmental factors, which includes mineral concentration. However, the association between mineral concentration and meat quality, and the specific molecular pathways underlying this association, are not well explored. We therefore analyzed gene expression as measured with RNA-seq in Longissimus thoracis muscle of 194 Nelore steers for association with three meat quality traits (intramuscular fat, meat pH, and tenderness) and the concentration of 13 minerals (Ca, Cr, Co, Cu, Fe, K, Mg, Mn, Na, P, S, Se, and Zn). We identified seven sets of co-expressed genes (modules) associated with at least two traits, which indicates that common pathways influence these traits. From pathway analysis of...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: AMPK pathway; Co-expression analysis; RNA sequencing; Tenderness; Gordura Animal; Gado de Corte; Intramuscular fat; Beef quality; Beef cattle.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1107117
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Differences in the skeletal muscle transcriptome profile associated with extreme values of fatty acids content. Repositório Alice
CESAR, A. S. M.; REGITANO, L. C. de A.; POLETI, M. D.; ANDRADE, S. C. da S.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; FELICIO, A. M.; NASCIMENTO, M. L. do; CHAVES, A. S.; LANNA, D. P. D.; TULLIO, R. R.; NASSU, R. T.; KOLTES, J. E.; WATERS, E. F.; MOURAO, G. B.; ZERLOTINI NETO, A.; REECY, J. M.; COUTINHO, L. L..
bitstream/item/153206/1/artigo5-Cesar-BMCGenomics-2016.pdf
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Bos Indicus; Human health; Lipids.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1060542
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Differentially expressed miRNAs in skeletal muscle related to feed efficiency in Nellore cattle. Repositório Alice
OLIVEIRA, P. S. N. de; TIZIOTO, P. C.; OLIVEIRA, G. B.; CESAR, A. S. M.; DINIZ, W. J. da S.; LIMA, A. O. de; REECY, J. M.; COUTINHO, L. L.; REGITANO, L. C. de A..
2016
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Bos indicus; Gene regulation; Residual feed intake; Bos indicus; Bos indicus.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1056602
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Evidence of miRNA regulation of intramuscular fat deposition in beef cattle. Repositório Alice
OLIVEIRA, G. B. de; CESAR, A. S. M.; FELÍCIO, A. M.; KAPPELER, B. I. G.; POLETI, M. D.; REGITANO, L. C. de A.; COUTINHO, L. L..
2016
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Gado de corte; Gado de corte; Beef cattle.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1057034
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Expression quantitative trait loci (eQTL) hotspot regions from whole genome analysis of Nellore steers. Repositório Alice
CESAR, A. S. M.; REGITANO, L. C. de A.; LANNA, D. P. D.; POLETI, M. D.; KOLTES, J. E.; REECY, J. M.; FRITZ-WATERS, E.; KRAMER, L.; GARRICK, D.; MUDADU, M. de A.; TULLIO, R. R.; COUTINHO, L. L..
2016
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Gado de corte; Nelore; Gado nelore; Nellore.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1057056
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Feed efficiency indexes and their relationships with carcass, non-carcass and meat quality traits in nellore steers. Repositório Alice
NASCIMENTO, M. L. do; SOUZA, A. R. D. L.; CHAVES, A. S.; CESAR, A. S. M.; TULLIO, R. R.; MEDEIROS, S. R. de; MOURAO, G. B.; ROSA, A. do N.; FEIJO, G. L. D.; ALENCAR, M. M. de; LANNA, D. P. D..
Five hundred and seventy-five Nellore steers were evaluated for residual feed intake and residual feed intake and gain and their relationships between carcass, non-carcass and meat quality traits. RFI was measured by the difference between observed and predicted dry matter intake and RIG was obtained by the sum of − 1*RFI and residual gain. Efficient and inefficient animals were classified adopting ± 0.5 standard deviations from RFI and RIG mean. A mixed model was used including RFI or RIG and contemporary group as fixed effects, initial age as covariate and sire and experimental period as random effects, testing the significance of the regression slope for each evaluated trait. RIG was positively related to longissimus muscle area. Efficient-RFI...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Meat quality; Nellore steers; Feed efficiency.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1065231
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Feed efficiency indexes and their relationships with carcass, non-carcass and meat quality traits in Nellore steers. Repositório Alice
NASCIMENTO, M. L.; SOUZA, A. R. D. L.; CHAVES, A. S.; CESAR, A. S. M.; TULLIO, R. R.; MEDEIROS, S. R. de; MOURÃO, G. B.; ROSA, A. do N.; FEIJO, G. L. D.; ALENCAR, M. M. de; LANNA, D. P. D..
Five hundred and seventy-five Nellore steerswere evaluated for residual feed intake and residual feed intake and gain and their relationships between carcass, non-carcass and meat quality traits. RFI was measured by the difference between observed and predicted dry matter intake and RIG was obtained by the sum of ?1*RFI and residual gain. Efficient and inefficient animals were classified adopting ±0.5 standard deviations from RFI and RIG mean. A mixed model was used including RFI or RIG and contemporary group as fixed effects, initial age as covariate and sire and experimental period as random effects, testing the significance of the regression slope for each evaluated trait. RIG was positively related to longissimus muscle area. Efficient-RFI animals had...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Internal fat; Visceral organs; Bos indicus; Gado zebu; Beef cattle; Zebu; Feed conversion; Meat tenderness.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1066238
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Gene co-expression analysis indicates potential pathways and regulators of beef tenderness in Nellore cattle. Repositório Alice
GONÇALVES, T. M.; REGITANO, L. C. de A.; KOLTES, J. E.; CESAR, A. S. M.; ANDRADE, S. C. da S.; MOURAO, G. B.; GASPARIN, G.; MOREIRA, G. C. M.; FRITZ-WATERS, E.; REECY, J. M.; COUTINHO, L. L..
Beef tenderness, a complex trait affected by many factors, is economically important to beef quality, industry, and consumer?s palatability. In this study, RNA-Seq was used in network analysis to better understand the biological processes that lead to differences in beef tenderness. Skeletal muscle transcriptional profiles from 24 Nellore steers, selected by extreme estimated breeding values (EBVs) for shear force after 14 days of aging, were analyzed and 22 differentially expressed transcripts were identified. Among these were genes encoding ribosomal proteins, glutathione transporter ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4), and synaptotagmin IV (SYT4). Complementary co-expression analyses using Partial Correlation with Information...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Qualidade da carne; Maciez da carne; Carne; Gado de Corte; Beef; Beef cattle; Beef quality.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1106256
Registros recuperados: 40
Primeira ... 12 ... Última
 

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