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Altered Levels of Nodal Excitability by Rate-Dependent Inhibitory Effects of Essential Oil of Citrus aurantium on the Electrophysiological Properties of Isolated Perfused Rabbit AV-Node: Protective Role in the Prevention of Ouabain Toxicity International Journal of Morphology
Khori,Vahid; Nayebpour,Mohsen; Mansourian,Azad Reza; Davarian,Ali; Naseri,Mohsen; Salehi,Aref; Alizadeh,Ali-Mohamad.
Treatment of supraventricular arrhythmia includes a wide range of medical interventions. Herbal remedies are suitable alternatives to synthetic drugs due to their availability, minimal side effects and lower price. Pharmacological studies and traditional medical literature point to the cardiovascular effects of Citrus aurantium L. (Rutaceae) in many instances. In the present study we used isolated perfused AV-node of rabbit as an experimental model to determine the effect of various concentrations of essential oil of C. aurantium (0.1-0.3 v/v) on the nodal conduction time and refractoriness of an isolated rabbit AV-nodal preparations. Selective stimulation protocols were used to independently quantify AV nodal recovery, facilitation and fatigue in 18...
Tipo: Journal article Palavras-chave: Citrus aurantium; Isolated AV-node; Arrhythmia; Herbal drugs.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000200019
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Can Formaldehyde Exposure Induce Histopathologic and Morphometric Changes on Rat Kidney? International Journal of Morphology
Golalipour,Mohammad Jafar; Azarhoush,Ramin; Ghafari,Soraya; Davarian,Ali; Fazeli,Seyyed Amirhossein.
Formaldehyde is used traditionally for fixing the cadaver, and vaporized during dissection and practical studying on cadaver. This study was designed to determine the histopathologic and morphometric changes of rat kidney while all of the experiments were exposed to formaldehyde for 18 weeks. 28 male albino Wistar rats were divided into the following three experimental groups (E1: 2hrs/d, 2d/w; E2: 2hrs/d, 4d/w; E3: 4hrs/d, 4d/w) and one control group (C). when the exposure period was expired the animals were anaesthetized with chloroform. After cervical dislocation, the abdomen was dissected and the kidneys were taken. The kidney specimens were sectioned and stained with Haematoxylin and Eosin technique for histologic and morphometric study. Data were...
Tipo: Journal article Palavras-chave: Formaldehyde; Exposure; Histology; Kidney; Rat; Morphometry.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400037
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Cardioprotective Effects of Exogenous and Endogenous Hydrocortisone in the Rabbit Model of Ischemia-Reperfusion International Journal of Morphology
Davarian,Ali; Khori,Vahid; Nayebpour,Mohsen.
Reducing the infarct size in acute myocardial infarction is one of the most important goals driving new drug research and development. During the last two decades, many clinical studies have found cardioprotective effects of corticosteroids, but their exact role in ischemic preconditioning remains questionable. The aim of the present study was to determine the protective effects of hydrocortisone sodium succinate on myocardial preconditioning in rabbit hearts. Twenty-four male New Zealand rabbits were divided randomly & equally in four groups: 1) control, 2) Infarct, 3) Ischemic preconditioning (IP) and 4) Hydrocortisone (HYD). The HYD group received 50mg/kg Hydrocortisone 45min before major ischemia. Serum levels of cardiac troponin-T(cTNT) and...
Tipo: Journal article Palavras-chave: Hydrocortisone; Infarct size; Ischemia-reperfusion model; Ischemic preconditioning; Serum cortisole.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000300001
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Histopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde Exposure International Journal of Morphology
Davarian,Ali; Fazeli,Seyyed Amirhossein; Azarhoush,Ramin; Jafar Golalipour,Mohammad.
Formaldehyde is a chemical, which is used traditionally for fixing the cadaver. It is vaporized during dissection and practical studying on cadaver. Studies show that this vapor can cause some clinical symptoms such as throat, eye, skin and nasal irritation. This study was designed to determine the histopathologic changes of rat tracheal mucosa while all of the experiments were exposed to formaldehyde for 18 weeks. This study was performed on 28, 6-7 weeks postnatal albino Wistar rats. The rats were divided into 3 case groups (E1: 4h/d, 4d/w; E2: 2h/d, 4d/w; E3: 2h/d, 2d/w) and 1 control group. The tracheal specimens were sectioned and stained with H&E technique for histopathologic study. An epithelial disorganization, cilia disappearance, slight...
Tipo: Journal article Palavras-chave: Formaldehyde exposure; Rat; Tracheal mucosa.
Ano: 2005 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000400013
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Morphometric Evidences for Regional Variation in Potential of Neural Plasticity International Journal of Morphology
Fazeli,Seyyed Amirhossein; Davarian,Ali; Behnampour,Naser; Golalipour,Mohammad Jafar.
The neural plasticity showing the ability of nervous system to change its structure and function is a well-documented fact. However regional variation within a CNS structure to undergo plastic changes has been shown by limited studies. Along medial-lateral sequences of parasagittal sections, the molecular layer thickness of primary fissure borderlands in rat cerebellar left hemisphere was studied to assess the regional difference in plasticibility. Despite the homogeneity of cerebellar histology, this study showed that there is a significant interlobular difference between ML thicknesses of Prf borderlands. In addition, it revealed that the thickness alters in a significant trend within each borderland. The quantitative heterogeneity of cerebellar...
Tipo: Journal article Palavras-chave: Plasticibility; Molecular layer; Primary fissure; Cerebellum; Rat.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000300010
Registros recuperados: 5
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