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Effects of water accommodated fractions of crude oils and diesel on a suite of biomarkers in Atlantic cod (Gadus morhua) ArchiMer
Holth, T. F.; Eidsvoll, D. P.; Farmen, E.; Sanders, M. B.; Martinez-gomez, C.; Budzinski, H.; Burgeot, Thierry; Guilhermino, L.; Hylland, K..
The aim of this study was to characterise concentration- and time-dependent responses in juvenile Atlantic cod (Gadus morhua) following exposure for one and three weeks to the water-soluble fraction (WAF) of three weathered oils: Arabian Light crude oil (ALC), North Sea crude oil (NSC) and ship-diesel. The sum of polycyclic aromatic hydrocarbons (PAH) in water was highest after one week of exposure and within environmentally relevant concentrations. PAH metabolites in bile confirmed exposure to and uptake of PAHs. Hepatic cytochrome P450 1A (CYP1A) gene expression (here and later the phrase gene expression is used synonymously to gene transcription, although it is acknowledged that gene expression is also regulated by, e.g., translation and protein...
Tipo: Text Palavras-chave: Atlantic cod; Biomarkers; Weathered crude oil; Ship-diesel; Water accommodated fraction; Time-course.
Ano: 2014 URL:
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