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Capecitabine maintenance therapy in patients with recurrent or metastatic breast cancer BJMBR
Si,W.; Zhu,Y.Y.; Li,Y.; Gao,P.; Han,C.; You,J.H.; Linghu,R.X.; Jiao,S.C.; Yang,J.L..
Our objective was to investigate the efficacy and safety of capecitabine maintenance therapy (CMT) after capecitabine-based combination chemotherapy in patients with metastatic breast cancer. The clinical data of 139 metastatic breast cancer patients treated from March 2008 to May 2012 with capecitabine-based combination chemotherapy were retrospectively analyzed. When initial disease control was achieved by the combination chemotherapy, we used CMT for 50 patients, while 37 patients were treated with a different (non-CMT) maintenance therapy. We compared time to progression (TTP), objective response rate, disease control rate, clinical benefit rate, and safety of the two groups, and a sub-group analysis was performed according to pathological...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Capecitabine; Maintenance therapy; Metastatic breast cancer.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001201074
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