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Blood compatibility assessments of electrospun polyurethane nanocomposites blended with megni oil for tissue engineering applications Anais da ABC (AABC)
JAGANATHAN,SARAVANA KUMAR; MANI,MOHAN P.; SUPRIYANTO,EKO.
Abstract: Tissue engineering holds as a prominent technique to repair or replace the damaged human parts to recreate its native function. In this research, a novel scaffold based on polyurethane (PU) comprising megni oil was electrospun for tissue engineering applications. The obtained polyurethane blended with megni oil nanofibers were characterized by scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), contact angle measurement and atomic force microscopy (AFM). Furthermore, the blood compatibility of the fabricated nanocomposites evaluated through activated prothrombin time (APTT), partial thromboplastin time (PT) and hemolysis assay to determine the anticoagulant nature. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Polyurethane; Megni oil; Electrospun scaffold; Blood compatibility; Tissue engineering.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300708
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Electrospinning synthesis and assessment of physicochemical properties and biocompatibility of cobalt nitrate fibers for wound healing applications Anais da ABC (AABC)
JAGANATHAN,SARAVANA KUMAR; MANI,MOHAN P..
Abstract: The aim of this study was to develop polyurethane (PU) wound dressing incorporated with cobalt nitrate using electrospinning technique. The morphology analysis revealed that the developed composites exhibited reduced fiber and pore diameter than the pristine PU. The electrospun membranes exhibited average porosity in the range of 67% - 71%. Energy-dispersive X-ray spectra (EDS) showed the presence of cobalt in the PU matrix. The interaction of cobalt nitrate with PU matrix was evident in Fourier transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA). The contact angle results indicated the improved wettability of the prepared PU/cobalt nitrate composites (82° ± 2) than the pure PU (100° ± 1). The incorporation of cobalt...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Polyurethane; Cobalt nitrate; Electrospun fibers; Skin tissue engineering; Physico-chemical characteristics; Bio compatibility.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500901
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Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering Anais da ABC (AABC)
JAGANATHAN,SARAVANA KUMAR; MANI,MOHAN P..
Abstract Ayurveda oil contains numerous source of biological constituents which plays an important role in reducing the pain relief caused during bone fracture. The aim of the study is to fabricate the polyurethane (PU) scaffold for bone tissue engineering added with ayurveda amla oil using electrospinning technique. Scanning Electron Microscopy (SEM) analysis showed that the fabricated nanocomposites showed reduced fiber diameter (758 ± 185.46 nm) than the pristine PU (890 ± 116.91 nm). Fourier Infrared Analysis (FTIR) revealed the existence of amla oil in the PU matrix by hydrogen bond formation. The contact angle results revealed the decreased wettability (116° ± 1.528) of the prepared nanocomposites compared to the pure PU (100° ± 0.5774). The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Polyurethane; Ayurveda oil; Electrospun scaffold; Blood compatibility; Bone tissue engineering.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000101101
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