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Application of genetically modified mosquitoes in national vector control programmes: thoughts on integrated control Frontis
Mnzava, A.; Curtis, C.F.; Manga, L.; Touré, Y.T..
Advances in transgenic technology have allowed the development of genetically transformed insects that have reduced ability to support the development of disease pathogens. The integration of this new method within national vector control programmes is indeed the biggest challenge, notwithstanding the current weak health systems in most disease-endemic countries (DECs) to efficiently apply vector control interventions. Moreover, where integration is considered, it is essential that reliable data are available on the multiple effects of the interventions. This should be done in parallel to the general strengthening of both human, technical, financial and physical resources at all levels of the national health system
Tipo: Conference proceedings
Ano: 2005 URL: http://library.wur.nl/ojs/index.php/frontis/article/view/1201
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Ethical, legal and social issues in the use of genetically modified vectors for disease control Frontis
Touré, Y.T.; Manga, L..
Genetic control of vectors may have an important role to play in the interruption of vector-borne disease transmission if the main biotechnological and implementation challenges are adequately addressed. Following the demonstration, in the laboratory, of the technical feasibility to develop transgenic mosquitoes unable to transmit malaria and dengue pathogens, the following actions will need to be taken in order to make this approach a control method applicable for public-health purposes: establish a proof of efficacy and safety to be approved by authorized biosafety and regulatory bodies before any experimental release; ensure the public and the media that this goal is desirable, feasible and can be accomplished safely; develop a plan to gather all the...
Tipo: Conference proceedings
Ano: 2005 URL: http://library.wur.nl/ojs/index.php/frontis/article/view/1203
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