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Antibody responses to keyhole limpet hemocyanin, lipopolysaccharide and Newcastle disease virus vaccine in F2 and backcrosses of White Leghorn lines selected for two different immune response traits Inra
Minozzi, G.; PARMENTIER, H.K.; NIEUWLAND, M.G.B.; Bed'Hom, B.; Minvielle, F.; Gourichon, D.; PINARD-VAN DER LAAN, M.H..
Planned crosses were designed to producean F2 and 2 backcross populations from 2 lines of WhiteLeghorn chickens previously selected over 10 generationsfor 2 different in vivo immune responses. The selectioncriteria applied on the 2 grandparental lines were as follows:high antibody response to Newcastle disease virusvaccine 3 wk after vaccination (ND3) and high cell-mediatedimmune response [response to phytohemagglutinin].Furthermore a control line was kept by randombreeding. The objective of the study was to estimate ifthe 2 selection criteria applied on the pure lines hadchanged the level of and type of immune (humoral) responseto a new antigen, keyhole limpet hemocyanin(KLH), in the various second-generation progeny groups.In addition, correlations...
Tipo: Journal Article Palavras-chave: PRIMARY ANTIBODY RESPONSE; CHICKEN; KEYHOLE LIMPET HMOCYANIN; SALMONELLA ENTERIDITIS-DERIVED LIPOPOLYSACCHARIDE; SELECTION.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2008781c73d2&uri=/notices/prodinra1/2008/08/
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Correlated effects of selection for immunity in White Leghorn chicken lines on natural antibodies and specific antibody responses to KLH and M. Butyricum Inra
Minozzi, G.; Parmentier; Grasteau, S.; Nieuwland; Bed'Hom, B.; Gourichon, D.; Minvielle, F.; Pinard-van der Laan.
Background The effect of selection for three general immune response traits onprimary antibody responses (Ab) to Mycobacterium butyricum or keyhole limpethemocyanin (KLH) was studied in four experimental lines of White Leghorn chicken.Birds underwent 12 generations of selection for one of three different general immunecriteria; high antibody response to Newcastle disease virus 3 weeks after vaccination(ND3), high cell-mediated immune response, using the wing web response tophytohemglutinin (PHA) and high phagocytic activity, measured as carbone clearance(CC). Line ND3-L was selected on ND3, line PHA-L was selected on PHA, and lineCC-L on CC, but all lines were measured for all three traits. The fourth line was...
Tipo: Journal Article Palavras-chave: WHITE LEGHORN CHICKEN BREED; MYCOBACTERIUM BUTYRICUM; SELECTION.
Ano: 2008 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD200839cc3331&uri=/notices/prodinra1/2009/11/
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