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Fasting differentially regulates plasma corticosterone-binding globulin, glucocorticoid receptor, and cell cycle in the gastric mucosa of pups and adult rats Inra
Ogias, D.; De Andrade Sá, E.R.; Kasai, A.; Moisan, M.P.; Alvares, E.P.; Gama, P..
The nutritional status influences gastric growth, and interestingly, whereas cell proliferation is stimulated by fasting in suckling rats, it is inhibited in adult animals. Corticosterone takes part in the mechanisms that govern development, and its effects are regulated in particular by corticosterone-binding globulin (CBG) and glucocorticoid receptor (GR). To investigate whether corticosterone activity responds to fasting and how possible changes might control gastric epithelial cell cycle, we evaluated different parameters during the progression of fasting in 18- and 40-day-old rats. Food restriction induced higher corticosterone plasma concentration at both ages, but only in pups did CBG binding increase after short- and long-term treatments. Fasting...
Tipo: Journal Article Palavras-chave: RESTRICTION ALIMENTAIRE; ÂGE; CORTICOSTERONE; RÉCEPTEUR GLUCOCORTICOÏDE; GLOBULINE; HORMONE; RÉGIME ALIMENTAIRE FOOD RESTRICTION; STOMACH.
Ano: 2010 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2010b80897ff&uri=/notices/prodinra1/2010/11/
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